A
Anja Schallon
Researcher at University of Bayreuth
Publications - 11
Citations - 600
Anja Schallon is an academic researcher from University of Bayreuth. The author has contributed to research in topics: Polyelectrolyte & Nanoparticle. The author has an hindex of 8, co-authored 11 publications receiving 565 citations. Previous affiliations of Anja Schallon include Helsinki University of Technology.
Papers
More filters
Journal ArticleDOI
Influence of Polymer Architecture and Molecular Weight of Poly(2-(dimethylamino)ethyl methacrylate) Polycations on Transfection Efficiency and Cell Viability in Gene Delivery
TL;DR: It is proposed that polymers with a branched architecture and an intermediate molecular weight are the most promising candidates for efficient gene delivery, since they combine low cytotoxicity with acceptable transfection results.
Journal ArticleDOI
Dual-responsive magnetic core-shell nanoparticles for nonviral gene delivery and cell separation.
Alexander P. Majewski,Anja Schallon,Valérie Jérôme,Ruth Freitag,Axel H. E. Müller,Holger Schmalz +5 more
TL;DR: The synthesis of dual-responsive (pH and temperature) magnetic core-shell nanoparticles utilizing the grafting-from approach led to a 2-fold increase in the transfection efficiency without increasing the cytotoxicity, as compared to polyethyleneimine (PEI), and yielded on average more than 50% transfected cells.
Journal ArticleDOI
Performance of three PDMAEMA-based polycation architectures as gene delivery agents in comparison to linear and branched PEI
Anja Schallon,Valérie Jérôme,Andreas Walther,Christopher V. Synatschke,Axel H. E. Müller,Ruth Freitag +5 more
TL;DR: AtRP (atom transfer radical polymerization) was used to synthesize three highly defined structures of PDMAEMA (linear, highly-branched, and star-shaped), which were systematically compared to linear and branched PEI to investigate intracellular trafficking and transfection efficiencies.
Journal ArticleDOI
Magnetic and fluorescent glycopolymer hybrid nanoparticles for intranuclear optical imaging.
André Pfaff,Anja Schallon,Thomas M. Ruhland,Alexander P. Majewski,Holger Schmalz,Ruth Freitag,Axel H. E. Müller +6 more
TL;DR: In this article, the synthesis of core-shell nanospheres exhibiting both fluorescent and magnetic properties by grafting a glycocopolymer consisting of 6-Omethacryloylgalactopyranose (MAGal) and 4-(pyrenyl)butyl methacrylate (PyMA) onto magnetic silica particles via thiol-ene chemistry is reported.
Journal ArticleDOI
Nanoparticulate nonviral agent for the effective delivery of pDNA and siRNA to differentiated cells and primary human T lymphocytes.
TL;DR: A novel type of PDMAEMA-based star-shaped nanoparticles are introduced that are efficient transfection agents in clinically relevant and difficult-to-transfect human cells and can efficiently deliver siRNA to human primary T lymphocytes resulting to more than 40% silencing of the targeted gene.