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Anna Gillio-Tos
Researcher at Cancer Epidemiology Unit
Publications - 46
Citations - 2977
Anna Gillio-Tos is an academic researcher from Cancer Epidemiology Unit. The author has contributed to research in topics: Cervical cancer & Colposcopy. The author has an hindex of 22, co-authored 44 publications receiving 2761 citations. Previous affiliations of Anna Gillio-Tos include University of Turin.
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Journal ArticleDOI
Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trial
Guglielmo Ronco,Paolo Giorgi-Rossi,Francesca Carozzi,Massimo Confortini,Paolo Palma,Annarosa Del Mistro,B. Ghiringhello,Salvatore Girlando,Anna Gillio-Tos,Laura De Marco,Carlo Naldoni,Paola Pierotti,Raffaella Rizzolo,Patrizia Schincaglia,Manuel Zorzi,Marco Zappa,Nereo Segnan,Jack Cuzick +17 more
TL;DR: HPV-based screening is more effective than cytology in preventing invasive cervical cancer, by detecting persistent high-grade lesions earlier and providing a longer low-risk period, but in younger women, HPV screening leads to over-diagnosis of regressive CIN2.
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Human Papillomavirus Testing and Liquid-Based Cytology: Results at Recruitment From the New Technologies for Cervical Cancer Randomized Controlled Trial
Guglielmo Ronco,Nereo Segnan,Paolo Giorgi-Rossi,Marco Zappa,Gian Piero Casadei,Francesca Carozzi,Paolo Dalla Palma,Annarosa Del Mistro,Stefania Folicaldi,Anna Gillio-Tos,Gaetano Nardo,Carlo Naldoni,Patrizia Schincaglia,Manuel Zorzi,Massimo Confortini,Jack Cuzick +15 more
TL;DR: HPV testing alone was more sensitive than conventional cytology among women 35-60 years old and HPV testing using Hybrid Capture 2 with a 2 pg/mL cutoff may be more appropriate than a 1 pg/ mL cutoff for primary cervical cancer screening.
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Results at Recruitment From a Randomized Controlled Trial Comparing Human Papillomavirus Testing Alone With Conventional Cytology as the Primary Cervical Cancer Screening Test
Guglielmo Ronco,Paolo Giorgi-Rossi,Francesca Carozzi,Massimo Confortini,Paolo Dalla Palma,Annarosa Del Mistro,Anna Gillio-Tos,Minucci D,Carlo Naldoni,Raffaella Rizzolo,Patrizia Schincaglia,Renza Volante,Marco Zappa,Manuel Zorzi,Jack Cuzick,Nereo Segnan +15 more
TL;DR: The large relative sensitivity of HPV testing compared with conventional cytology and the difference between relative sensitivity during phases 1 and 2 suggests that there is frequent regression of CIN2+ that are detected by direct referral of younger HPV-positive women to colposcopy.
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Use of p16-INK4A overexpression to increase the specificity of human papillomavirus testing: a nested substudy of the NTCC randomised controlled trial.
Francesca Carozzi,Massimo Confortini,Paolo Palma,Annarosa Del Mistro,Anna Gillio-Tos,Laura De Marco,Paolo Giorgi-Rossi,Giovanni Pontenani,Stefano Rosso,Cristina Sani,Catia Sintoni,Nereo Segnan,Manuel Zorzi,Jack Cuzick,Raffaella Rizzolo,Guglielmo Ronco +15 more
TL;DR: HPV testing with p16-INK4A triage produces a significant increase in sensitivity compared with conventional cytology, with no substantial increase in referral to colposcopy.
Journal ArticleDOI
Risk of high-grade cervical intraepithelial neoplasia during follow-up in HPV-positive women according to baseline p16-INK4A results: a prospective analysis of a nested substudy of the NTCC randomised controlled trial
Francesca Carozzi,Anna Gillio-Tos,Massimo Confortini,Annarosa Del Mistro,Cristina Sani,Laura De Marco,Salvatore Girlando,Stefano Rosso,Carlo Naldoni,Paolo Palma,Manuel Zorzi,Paolo Giorgi-Rossi,Nereo Segnan,Jack Cuzick,Guglielmo Ronco +14 more
TL;DR: The relation between p16 status and risk of CIN during 3 years of follow-up was investigated and the relative sensitivity of an alternative strategy versus conventional cytology in two age groups was assessed.