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Showing papers by "Anna Karin Lindroos published in 1998"


Journal ArticleDOI
TL;DR: It is concluded that during early recovery from hyperthyroidism, priority is given to the replenishment of skeletal muscles and ip AT, whereas sc AT is increased at a later stage.
Abstract: Body composition changes in nine adults with hyperthyroidism were determined with dual energy x-ray absorptiometry and computed tomography at diagnosis and after 3 and 12 months of euthyroidism achieved by surgery, antithyroid drugs, or treatment with radioiodine. Mean body weight was 67.6 kg at diagnosis and increased 2.7 kg (P=0.06) and 8.7 kg (P < 0.001) after 3 and 12 months of euthyroidism, respectively. Basal metabolic rate decreased from 2087 Cal/24 h at diagnosis to 1601 Cal/24 h at 12 months (P=0.001), whereas reported energy intake dropped from 3244 to 2436 Cal/24 h (P=0.01). According to dual energy x-ray absorptiometry, body fat was unchanged at 3 months, but increased by 5.3 kg (P < 0.0001) at 12 months. Fat-free mass increased 2.7 kg (P=0.003) at 3 months and 3.5 kg (P < 0.0001) at 12 months. Changes in bone mineral content and density did not reach significance. According to computed tomography, skeletal muscle plus skin areas increased by 11% (trunk) and 18% (thigh) at 3 months and by 17% (trunk) and 25% (thigh) at 12 months. There was no increase in sc adipose tissue (AT) at 3 months, but at 12 months this AT depot increased by 15% (thigh) and 33% (trunk). Intraperitoneal AT showed a borderline significant increase by 28% (P=0.08) at 3 months and by 40% (P=0.015) at 12 months. Areas of visceral organs and bone tissue of femur did not change significantly during the study. It is concluded that during early recovery from hyperthyroidism, priority is given to the replenishment of skeletal muscles and ip AT, whereas sc AT is increased at a later stage.

83 citations


Journal ArticleDOI
01 May 1998
TL;DR: Obesity will be presented as an example of a condition that can introduce bias in population-based surveys, as well as in clinical studies describing the obese condition.
Abstract: Experimental as well as epidemiological nutrition studies often aim at measuring food intake and its correlates in ‘free-living’ human subjects, and the identification of optimal ways to do this is a challenge in both types of research. The purpose of the present paper is, first, to give a brief overview of general problems encountered in measuring intake in free-living human subjects. Focus will then be placed on issues involving assessment of nutritional exposures in observational epidemiology, a field that is vulnerable to many sources of measurement error. Finally, obesity will be presented as an example of a condition that can introduce bias in population-based surveys, as well as in clinical studies describing the obese condition.

66 citations