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Anna Ramírez-Soriano
Researcher at Pompeu Fabra University
Publications - 13
Citations - 742
Anna Ramírez-Soriano is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Neutral theory of molecular evolution & Population. The author has an hindex of 9, co-authored 13 publications receiving 699 citations. Previous affiliations of Anna Ramírez-Soriano include Spanish National Research Council.
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Statistical Power Analysis of Neutrality Tests Under Demographic Expansions, Contractions and Bottlenecks With Recombination
TL;DR: It is shown that tests that rely on haplotype frequencies are the most powerful for detecting expansions on nonrecombining genomic regions and should not be used when recombination levels are unknown, so class I tests, particularly Tajima's D or R2, are recommended.
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Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes
Anna Ferrer-Admetlla,Elena Bosch,Martin Sikora,Tomas Marques-Bonet,Anna Ramírez-Soriano,Aura Muntasell,Arcadi Navarro,Ross Lazarus,Francesc Calafell,Jaume Bertranpetit,Ferran Casals +10 more
TL;DR: This study analyzes the variability patterns in different human populations of fifteen genes related to innate immunity and finds some signatures of positive and especially balancing selection in these genes, thus confirming the importance of the immune system genetic plasticity in the evolutionary adaptive process.
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Evolutionary dynamics of the human ABO gene
Francesc Calafell,Francis Roubinet,Anna Ramírez-Soriano,Naruya Saitou,Jaume Bertranpetit,Antoine Blancher +5 more
TL;DR: The ABO polymorphism has long been suspected to be under balancing selection, and a phylogenetic analysis of the Seattle sequences showed a complex pattern in which the action of recombination and gene conversion are evident, and in which four main lineages could be individuated.
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The prion protein gene in humans revisited: Lessons from a worldwide resequencing study
Marta Soldevila,Aida M. Andrés,Anna Ramírez-Soriano,Tomas Marques-Bonet,Francesc Calafell,Arcadi Navarro,Jaume Bertranpetit +6 more
TL;DR: The analyses reveal the worldwide pattern of variation at the PRNP gene to be inconsistent with neutral expectations, indicating instead an excess of low-frequency variants, a footprint of the action of either positive or purifying selection.
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Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene
Andrés Moreno-Estrada,Ferran Casals,Anna Ramírez-Soriano,Baldo Oliva,Francesc Calafell,Jaume Bertranpetit,Elena Bosch +6 more
TL;DR: Molecular structural inference suggests that one of the nonsynonymous polymorphisms defining the presumably adaptive protein form of OR5I1 may alter the functional binding properties of the OR, compatible with positive selection and with a relatively ancient, mild selective sweep predating the "Out of Africa" expansion of modern humans.