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Anthony C. Allison
Researcher at University of London
Publications - 79
Citations - 7058
Anthony C. Allison is an academic researcher from University of London. The author has contributed to research in topics: Adjuvant & Antigen. The author has an hindex of 39, co-authored 79 publications receiving 6853 citations.
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Journal ArticleDOI
Mycophenolate mofetil and its mechanisms of action.
TL;DR: The efficacy of regimes including CellCept(R) in preventing allograft rejection, and in the treatment of rejection, is now firmly established and it is hoped that the drug will have the same effect in humans.
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Liposomes as immunological adjuvants
TL;DR: There is real need for a safe and effective adjuvant for use in human immunisation programmes, for example, Freund's incomplete adjUvant, a water-in-oil emulsion containing the antigen.
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Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA
Simon W. Lee,Ann-ping Tsou,Hardy W. Chan,Jan Thomas,Karen Petrie,Elsie M. Eugui,Anthony C. Allison +6 more
TL;DR: Inhibition of the formation and effects IL-1 is a mechanism by which glucocorticoids can exert antiinflammatory and immunosuppressive effects and kinetic analyses and pulse-labeling of mRNAs showed that glucoc Corticoids selectively decrease the stability of IL- 1 beta mRNA, without affecting the stabilityof beta-actin and FOS mRN as.
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Measurement of interleukin-1 alpha and -1 beta in gingival crevicular fluid: implications for the pathogenesis of periodontal disease.
TL;DR: It is demonstrated that IL-1 is produced and released locally in periodontal disease at concentrations sufficient to mediate tissue inflammation and bone resorption and may serve as a marker ofperiodontal tissue destruction.
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An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity
TL;DR: The development of an adjuvant formulation able to elicit the formation of protective antibodies and CMI without unacceptable side effects is described.