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Anton Goussev
Researcher at Henry Ford Health System
Publications - 29
Citations - 3089
Anton Goussev is an academic researcher from Henry Ford Health System. The author has contributed to research in topics: Traumatic brain injury & Morris water navigation task. The author has an hindex of 27, co-authored 29 publications receiving 2978 citations. Previous affiliations of Anton Goussev include Henry Ford Hospital & Ford Motor Company.
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Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia.
Zheng Gang Zhang,Li Zhang,Wayne Tsang,Hamid Soltanian-Zadeh,Daniel C. Morris,Ruilan Zhang,Anton Goussev,Cecylia Powers,Thomas Yeich,Michael Chopp,Michael Chopp +10 more
TL;DR: Analysis of the spatial and temporal profiles of blood–brain barrier leakage, angiogenesis, vascular endothelial growth factor (VEGF), associated receptors, and angiopoietins and receptors after embolic stroke in the rat suggests that acute alteration of VEGF and Ang 1 in the ischemic core may mediate BBB leakage, whereas upregulation of V EGF/VEGF receptors and Ang/Tie2 at the boundary zone may regulate neovascularization in ische
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Erythropoietin enhances neurogenesis and restores spatial memory in rats after traumatic brain injury
Dunyue Lu,Asim Mahmood,Changsheng Qu,Anton Goussev,Timothy J Schallert,Michael Chopp,Michael Chopp +6 more
TL;DR: The data suggest that EPO treatment initiated 1 day after TBI is neurorestorative by enhancing neurogenesis, as well as neuroprotective.
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Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
Dunyue Lu,Changsheng Qu,Anton Goussev,Hao Jiang,Chang Lu,Timothy J Schallert,Timothy J Schallert,Asim Mahmood,Jieli Chen,Yi Li,Michael Chopp,Michael Chopp +11 more
TL;DR: Treatment of TBI with statins improves spatial learning and neurogenesis in rats subjected to controlled cortical impact and provides a therapeutic effect superior to treatment with atorvastatin, suggesting that statins may be candidates for treatment ofTBI.
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Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury.
TL;DR: Atorvastatin administration after brain injury significantly reduced the neurological functional deficits, increased neuronal survival and synaptogenesis in the boundary zone of the lesion and in the CA3 regions of the hippocampus, and induced angiogenesis in these regions.
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Cerebral vessels express interleukin 1β after focal cerebral ischemia
TL;DR: An early bilateral expression of IL-1beta on endothelium after MCA occlusion in mice is demonstrated and found on endothelial cells and microglia.