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Aoibheann Walsh
Researcher at University College Dublin
Publications - 1
Citations - 125
Aoibheann Walsh is an academic researcher from University College Dublin. The author has contributed to research in topics: Downregulation and upregulation & microRNA. The author has an hindex of 1, co-authored 1 publications receiving 104 citations.
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Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells.
Karolina Weiner-Gorzel,Eugene M. Dempsey,Malgorzata Milewska,Aloysius McGoldrick,Valerie Toh,Aoibheann Walsh,Sinéad Lindsay,Luke Gubbins,Aoife Cannon,Daniel J. Sharpe,Jacintha O'Sullivan,Madeline Murphy,Stephen F. Madden,Malcolm R. Kell,Amanda McCann,Fiona Furlong +15 more
TL;DR: Stable miR‐433 expression in A2780 OC cells results in the induction of cellular senescence demonstrated by morphological changes, downregulation of phosphorylated retinoblastoma (p‐Rb), and an increase in β‐galactosidase activity.