A
Arie van der Ende
Researcher at University of Amsterdam
Publications - 220
Citations - 8251
Arie van der Ende is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Meningitis & Neisseria meningitidis. The author has an hindex of 47, co-authored 220 publications receiving 7062 citations.
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Journal ArticleDOI
Community-acquired bacterial meningitis in adults in the Netherlands, 2006-14: a prospective cohort study
Merijn W Bijlsma,Matthijs C. Brouwer,E. Soemirien Kasanmoentalib,Anne T. Kloek,Marjolein J. Lucas,Michael W.T. Tanck,Arie van der Ende,Diederik van de Beek +7 more
TL;DR: The incidence of adult bacterial meningitis has decreased substantially, which is partly explained by herd protection by paediatric conjugate vaccines.
Journal ArticleDOI
Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model
Kin Ki Jim,Kin Ki Jim,Joo Yeon Engelen-Lee,Astrid M. van der Sar,Wilbert Bitter,Matthijs C. Brouwer,Arie van der Ende,Jan-Willem Veening,Diederik van de Beek,Christina M. J. E. Vandenbroucke-Grauls +9 more
TL;DR: A pneumococcal meningitis model in zebrafish embryos that allows for real-time investigation of early host-microbe interaction and time-lapse imaging revealed that the initial innate immune response to S. pneumoniae in the subarachnoid space mainly consisted of neutrophils and that pneumolysin-mediated cytolytic activity caused a marked reduction of phagocytes.
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Quasispecies Development of Helicobacter pylori Observed in Paired Isolates Obtained Years Apart from the Same Host
Ernst J. Kuipers,Dawn A. Israel,Johannes G. Kusters,Monique M. Gerrits,Jan Weel,Arie van der Ende,René W. M. van der Hulst,Hans Peter Wirth,Johanna Höök-Nikanne,Stuart A. Thompson,Martin J. Blaser +10 more
TL;DR: The changes detected by RAPD-PCR and AFLP indicate that genetic drift occurs within H. pylori populations over the course of years of colonization of a single host.
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Effects of pneumococcal conjugate vaccine 2 years after its introduction, the Netherlands.
Gerwin D. Rodenburg,Sabine C. de Greeff,Angelique G. C. S. Jansen,Hester E. de Melker,Leo M. Schouls,Eelko Hak,Lodewijk Spanjaard,Elisabeth A. M. Sanders,Arie van der Ende +8 more
TL;DR: Vaccine-serotype disease decreased, but non–vaccine-Serotype disease increased in 2016.
Journal ArticleDOI
Invasive pneumococcal disease among adults: associations among serotypes, disease characteristics, and outcome.
Angelique G S C Jansen,Gerwin D. Rodenburg,Arie van der Ende,Loek van Alphen,Reinier H. Veenhoven,Lodewijk Spanjaard,Elisabeth A. M. Sanders,Eelko Hak,Eelko Hak,Eelko Hak +9 more
TL;DR: The serotype appeared to be independently associated with IPD severity in adults, which indicates that careful monitoring of IPD after implementation of conjugate vaccines is necessary.