A
Arjumand Ather
Researcher at University of Tromsø
Publications - 22
Citations - 1011
Arjumand Ather is an academic researcher from University of Tromsø. The author has contributed to research in topics: Quantitative structure–activity relationship & Tyrosinase. The author has an hindex of 12, co-authored 22 publications receiving 948 citations. Previous affiliations of Arjumand Ather include University of Karachi & University of Ferrara.
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Tyrosinase inhibitory cycloartane type triterpenoids from the methanol extract of the whole plant of Amberboa ramosa Jafri and their structure–activity relationship
TL;DR: Eight new tyrosinase inhibitory cycloartane triterpenoids have been discovered from the methanol extract of the whole plant of Amberboa ramosa (Roxb.) Jafri, which is a member from the Compositae family.
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Prediction of Tyrosinase Inhibition Activity Using Atom‐Based Bilinear Indices
Yovani Marrero-Ponce,Yovani Marrero-Ponce,Mahmud Tareq Hassan Khan,Mahmud Tareq Hassan Khan,Gerardo M. Casañola Martín,Gerardo M. Casañola Martín,Arjumand Ather,M. N. Sultankhodzhaev,Francisco Torrens,Richard Rotondo +9 more
TL;DR: The results of QSAR studies of tyrosinase inhibitors using the new MDs and linear discriminant analysis (LDA) demonstrate the ability of the bilinear indices in testing biological properties, as well as proposing a new means of molecular parametrization easily calculated from 2D molecular information.
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Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by Bangladeshi natural plant extracts.
Elizabeth Lambertini,Ilaria Lampronti,Letizia Penolazzi,Mahmud Tareq Hassan Khan,Arjumand Ather,Gianluca Giorgi,Roberto Gambari,Roberta Piva +7 more
TL;DR: Lupeol, a known triterpenoid, was found to stimulate the decoy effect of RA4 DNA sequence, increasing at a high level ERa gene expression in MDA-MB-231 ERalpha-negative breast cancer cells, and also inhibited cell proliferation.
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Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kappaB binding sites.
Ilaria Lampronti,Mahmud Tareq Hassan Khan,Nicoletta Bianchi,Arjumand Ather,Monica Borgatti,L. Vizziello,Enrica Fabbri,Roberto Gambari +7 more
TL;DR: Low concentrations of Hemidesmus indicus, Polyalthia longifolia, Moringa oleifera and Lagerstroemia speciosa, and very low concentrations of Aphanamixis polystachya extracts inhibit the interactions between nuclear factors and target DNA elements mimicking sequences recognized by the nuclear factor kappaB (NF-kappaB).
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Bond-based 2D TOMOCOMD-CARDD approach for drug discovery: aiding decision-making in ‘in silico’ selection of new lead tyrosinase inhibitors
Yovani Marrero-Ponce,Yovani Marrero-Ponce,Mahmud Tareq Hassan Khan,Mahmud Tareq Hassan Khan,Gerardo M. Casañola-Martin,Gerardo M. Casañola-Martin,Arjumand Ather,M. N. Sultankhodzhaev,Ramón García-Domenech,Francisco Torrens,Richard Rotondo +10 more
TL;DR: A new set of bond-level TOMOCOMD-CARDD molecular descriptors (MDs) based on a bilinear map similar to those defined in linear algebra is presented, which could help to shed some clues in the identification of new chemicals that inhibits enzyme tyrosinase, for entering in the pipeline of drug discovery development.