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Åsa Björndal
Researcher at Karolinska Institutet
Publications - 14
Citations - 2502
Åsa Björndal is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 12, co-authored 14 publications receiving 2448 citations.
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Journal ArticleDOI
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.
Gabriella Scarlatti,Eleonora Tresoldi,Åsa Björndal,Robert Fredriksson,Claudia Colognesi,Hongkui Deng,Mauro S. Malnati,Anna Plebani,Antonio G. Siccardi,Dan R. Littman,Eva Maria Fenyö,Paolo Lusso +11 more
TL;DR: A consistent pattern of evolution of viral co-receptor usage and sensitivity to chemokine-mediated suppression in a longitudinal follow-up of children with progressive HIV-1 infection is document.
Journal ArticleDOI
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.
Åsa Björndal,Hongkui Deng,Marianne Jansson,Josè Ramòn Fiore,Claudia Colognesi,Anders Karlsson,Jan Albert,Gabriella Scarlatti,Dan R. Littman,Eva Maria Fenyö +9 more
TL;DR: All 36 well-characterized primary HIV-1 isolates induce syncytia, provided that target cells carry the particular coreceptor required by the virus, similar to the original population.
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Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates, Like HIV-1 Isolates, Frequently Use CCR5 but Show Promiscuity in Coreceptor Usage
Andreas Mörner,Åsa Björndal,Jan Albert,Vineet N. KewalRamani,Dan R. Littman,Rie Inoue,Rigmor Thorstensson,Eva Maria Fenyö,Ewa Björling +8 more
TL;DR: It is suggested that HIV-2 can use BOB when entering MT-2 cells, and the results indicate no obvious link between viral virulence and the ability to use a multitude of coreceptors.
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Differences in chemokine coreceptor usage between genetic subtypes of HIV-1.
Charlotte Tscherning,Annette Alaeus,Robert Fredriksson,Åsa Björndal,Hongkui Deng,Dan R. Littman,Eva Maria Fenyö,Jan Albert +7 more
TL;DR: This study shows that CXCR4 usage determines the biological phenotype for all subtypes, but that there appear to exist subtype-dependent differences in frequency of usage of certain coreceptors, opening up the possibility that genetic subtypes may differ in important biological properties such as virulence, tissue tropism, and transmissibility.
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Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of Ethiopian AIDS patients.
TL;DR: Comparative studies revealed that the scarcity of CXCR4 usage as well as other phenotypic characteristics of subtype C isolates distinguish this subtype.