A
Aydın Aktaş
Researcher at İnönü University
Publications - 56
Citations - 732
Aydın Aktaş is an academic researcher from İnönü University. The author has contributed to research in topics: Carbene & PEPPSI. The author has an hindex of 11, co-authored 49 publications receiving 475 citations. Previous affiliations of Aydın Aktaş include Karadeniz Technical University.
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Journal ArticleDOI
2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties
Fatoş Erdemir,Duygu Barut Celepci,Aydın Aktaş,Parham Taslimi,Yetkin Gök,Hasan Karabıyık,İlhami Gülçin +6 more
TL;DR: This study contains novel a serie synthesis of N-heterocyclic carbene (NHC) precursors that 2-hydroxyethyl substituted that effectively inhibited the α-glycosidase, cytosolic carbonic anhydrase I and II isoforms, butyrylcholinesterase (BChE) and acetylcholinease (AChE).
Journal ArticleDOI
Synthesis, characterization and crystal structure of 2-(4-hydroxyphenyl)ethyl and 2-(4-nitrophenyl)ethyl Substituted Benzimidazole Bromide Salts: Their inhibitory properties against carbonic anhydrase and acetylcholinesterase
Ayten Behçet,Tuba Çağlılar,Duygu Barut Celepci,Aydın Aktaş,Parham Taslimi,Yetkin Gök,Muhittin Aygün,Ruya Kaya,Ruya Kaya,İlhami Gülçin +9 more
TL;DR: In this article, the synthesis of 2-(4-hydroxyphenyl)ethyl and 2-nitrophenyl)-ethyl substituted benzimidazolium salts (1, 2a-g, and 3a-f) was reported.
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meta‐Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, α‐glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties
Ferhat Türker,Duygu Barut Celepci,Aydın Aktaş,Parham Taslimi,Yetkin Gök,Muhittin Aygün,İlhami Gülçin +6 more
TL;DR: The derivatives of these novel NHC precursors were effective inhibitors of α‐glycosidase (AG), the cytosolic carbonic anhydrase I and II isoforms, butyrylcholinesterase (BChE), and acetylcholinerase (AChE) with Ki values in the range of 1.01–2.18.
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Novel N-propylphthalimide- and 4-vinylbenzyl-substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and inhibition profiles against acetylcholinesterase and carbonic anhydrase enzymes
TL;DR: The novel N‐propylphthalimide‐substituted and 4‐vinylbenzyl‐subSTituted N‐heterocyclic carbene (NHC) precursors were synthesized by N‐subStituted benzimidazolium with aryl halides and demonstrated efficient inhibition profiles with Ki values in the range of 351.0–1269.6 nM.
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Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag(I)NHC coordination compounds
TL;DR: In this paper, the synthesis of N-phthalimidomethyl-substituted NHC precursors and their Ag(I)NHC coordination compounds were presented.