Medicinal plants of India with anti-diabetic potential.

Moringa oleifera, or the horseradish tree, is a pan-tropical species that is known by such regional names as benzolive, drumstick tree, kelor, marango, mlonge, mulangay, nebeday, saijhan, and sajna. Over the past two decades, many reports have appeared in mainstream scientific journals describing its nutritional and medicinal properties. Its utility as a non-food product has also been extensively described, but will not be discussed herein, (e.g. lumber, charcoal, fencing, water clarification, lubricating oil). As with many reports of the nutritional or medicinal value of a natural product, there are an alarming number of purveyors of “healthful” food who are now promoting M. oleifera as a panacea. While much of this recent enthusiasm indeed appears to be justified, it is critical to separate rigorous scientific evidence from anecdote. Those who charge a premium for products containing Moringa spp. must be held to a high standard. Those who promote the cultivation and use of Moringa spp. in regions where hope is in short supply must be provided with the best available evidence, so as not to raise false hopes and to encourage the most fruitful use of scarce research capital. It is the purpose of this series of brief reviews to: (a) critically evaluate the published scientific evidence on M. oleifera, (b) highlight claims from the traditional and tribal medicinal lore and from non-peer reviewed sources that would benefit from further, rigorous scientific evaluation, and (c) suggest directions for future clinical research that could be carried out by local investigators in developing regions.

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Moringa oleifera: A Review of the Medical Evidence for Its Nutritional, Therapeutic, and Prophylactic Properties. Part 1.

Pharmacological actions and potential uses of Momordica charantia: a review

Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats

http://biostevera.com/wp-content/uploads/2014/11/02-Comprehensive-review.pdf

Stevia rebaudiana Bertoni, source of a high-potency natural sweetener: A comprehensive review on the biochemical, nutritional and functional aspects

Preliminary studies on the inorganic constituents of some indigenous hypoglycaemic herbs on oral glucose tolerance test.

Essential micro-nutrients content of some common Indian spices and role of their inorganic mineral parts on oral glucose - tolerance test.

Background: Health issues are linked to gestational diabetes mellitus (GDM) in both the mother and the foetus. Adipose tissue (AT) health issues and obesity are linked to the emergence of GDM. Recent research has nevertheless demonstrated that decreased AT health can exist even in the absence of fat. In this study, we investigated whether AT health influences the onset of GDM in non-obese women.
 Method: GDM-diagnosed expectant mothers were examined. Non-GDM women with matching BMI and age served as the Controls (n=6 per group). Before and during cesarian sections, samples of AT and fasting blood were taken, respectively. Using the Bioplex assay, the serum levels of adiponectin were determined. Western blotting was used to quantify the expression of phosphorylated p38 (p-p38) in AT, and average adipocyte size values were calculated. Two-tailed unequal variance was used to determine the differences in the variables between the groups. P < .0 was regarded as statistically significant for the Student t test.
 Results: The pre-pregnancy BMI and age did not differ. The serum level of adiponectin was considerably lower in the GDM group. p-AT p38's expression, however, was noticeably higher. In the GDM group, the adipocyte size was 11% smaller, but the difference did not statistically vary from zero.
 Conclusion: Our findings show that among non-obese women, the development of GDM may be significantly influenced by AT health. Future research is necessary to identify the pathways via which AT health, in the absence of obesity, contributes to the development of GDM.
 
 
 A.K.Sinha: None. B.B.Bharti: None. B.K.Choudhary: None. P.Hans: None.


1834-PUB: Gestational Diabetes Mellitus in Nonobese Women Is Associated with Adipose Tissue Health

Monitoring and assessment of anthropogenic impacts on water quality by estimating the BMWP and ASPT indices for a headwater stream in Doon Valley, India

B.K Choudhary

Papers

Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats

Preliminary studies on the inorganic constituents of some indigenous hypoglycaemic herbs on oral glucose tolerance test.

Essential micro-nutrients content of some common Indian spices and role of their inorganic mineral parts on oral glucose - tolerance test.

1834-PUB: Gestational Diabetes Mellitus in Nonobese Women Is Associated with Adipose Tissue Health

Monitoring and assessment of anthropogenic impacts on water quality by estimating the BMWP and ASPT indices for a headwater stream in Doon Valley, India