B
B König
Researcher at University of Freiburg
Publications - 2
Citations - 417
B König is an academic researcher from University of Freiburg. The author has contributed to research in topics: Transducin & Rhodopsin. The author has an hindex of 2, co-authored 2 publications receiving 413 citations.
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Three cytoplasmic loops of rhodopsin interact with transducin
TL;DR: The sites of interaction of rhodopsin with its G protein are mapped, which by analogy suggests how other members of this class of receptors may interact with their G proteins.
Journal ArticleDOI
Displacement of rhodopsin by GDP from three-loop interaction with transducin depends critically on the diphosphate beta-position.
M Kahlert,B König,K.P. Hofmann +2 more
TL;DR: Results indicate a critical role of the beta-phosphate interaction with the nucleotide binding site in the GDP-induced transformation of Gt, and suggest a generalized induced fit mechanism, where MII induces opening of the Gt nucleotide site and release of GDP is obligatory to establish the MII-stabilizing rhodopsin-Gt three-loop interaction.