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Baihua Xu
Researcher at Chinese Academy of Sciences
Publications - 25
Citations - 459
Baihua Xu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Aryl & Substituent. The author has an hindex of 12, co-authored 25 publications receiving 443 citations. Previous affiliations of Baihua Xu include Hunan Normal University.
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Patent
Process for the preparation of benzylbenzene sglt2 inhibitors
TL;DR: In this article, methods of making compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT were provided. But they did not specify the type of compounds to be used.
Journal ArticleDOI
An efficient method for synthesis of bexagliflozin and its carbon-13 labeled analogue
TL;DR: A convenient method for highly diastereoselective synthesis of bexagliflozin 7a and its carbon-13 labeled analogue 7b was developed, which has the main feature is the stereoselectives reduction of 16 catalyzed by BF3·OEt2.
Patent
Preparation of hydroxy-benzylbenzene derivatives
TL;DR: Methods for preparing intermediates of SGLT2 inhibitors are provided in this paper, including crystalline forms and methods of crystallizing intermediates, and they are shown to work well in the presence of high temperature.
Journal ArticleDOI
DMP-Mediated One-Pot Oxidative Olefination of Silyl Ethers.
TL;DR: Silyl ethers of arylic, allylic, propargylic and unactivated alcohols could be deprotected and oxidized with Dess-Martin periodinane, and the resulting aldehydes could be directly converted to the corresponding α,β-unsaturated esters in one pot with stabilized phosphoranes as mentioned in this paper.
Patent
Procédé de préparation d'inhibiteurs du cotransporteur de glucose 2 dépendant du benzylbenzène sodium (sglt2)
TL;DR: In this article, a procedure de preparation de composes is described, which concerne des procedes de preparation of composes ayant un effet inhibiteur sur le cotransporteur du glucose dependant du sodium (SGLT) and des intermediaires de synthese utiles for the preparation desdits composes.