B
Bao-Shan Ku
Researcher at Peking University
Publications - 9
Citations - 1165
Bao-Shan Ku is an academic researcher from Peking University. The author has contributed to research in topics: Curcumin & Behavioural despair test. The author has an hindex of 8, co-authored 9 publications receiving 1079 citations.
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Journal ArticleDOI
Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB.
TL;DR: The results provide compelling evidence that the behavioral effects of curcumin in chronically stressed animals, and by extension humans, may be related to their modulating effects on the HPA axis and neurotrophin factor expressions.
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Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats.
TL;DR: The results suggested that curcumin administration increased hippocampal neurogenesis in chronically stressed rats, similar to classic antidepressant imipramine treatment, and demonstrated that these new cells mature and become neurons, as determined by triple labeling for BrdU and neuronal- or glial-specific markers.
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Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats
TL;DR: The results confirm the antidepressant effects of curcumin in the forced swim and the OB models of depression in rats, and suggest that these antidepressant effects may be mediated by actions in the central monoaminergic neurotransmitter systems.
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The effects of curcumin on depressive-like behaviors in mice.
TL;DR: The results suggest that the antidepressant-like effects of curcumin may involve the central monoaminergic neurotransmitter systems.
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Antidepressant-like effect of low molecular proanthocyanidin in mice: involvement of monoaminergic system.
Ying Xu,Shan Li,Shan Li,Ruijie Chen,Gaowen Li,Philip A. Barish,Wenting You,Ling Chen,Mengmeng Lin,Bao-Shan Ku,Jianchun Pan,William O. Ogle +11 more
TL;DR: The results suggested that oral administration proanthocyanidin at doses of 25 and 50mg/kg for 7days significantly reduced the duration of immobility in both the tail suspension and forced swimming tests, and suggest that the antidepressant-like effects of proanthopyridine may involve the central monoaminergic neurotransmitter systems.