Context Uncertainties continue about the roles that methodological factors and key risk factors, particularly torture and other potentially traumatic events (PTEs), play in the variation of reported prevalence rates of posttraumatic stress disorder (PTSD) and depression across epidemiologic surveys among postconflict populations worldwide. Objective To undertake a systematic review and meta-regression of the prevalence rates of PTSD and depression in the refugee and postconflict mental health field. Data Sources An initial pool of 5904 articles, identified through MEDLINE, PsycINFO and PILOTS, of surveys involving refugee, conflict-affected populations, or both, published in English-language journals between 1980 and May 2009. Study Selection Surveys were limited to those of adult populations (n ≥ 50) reporting PTSD prevalence, depression prevalence, or both. Excluded surveys comprised patients, war veterans, and civilian populations (nonrefugees/asylum seekers) from high-income countries exposed to terrorist attacks or involved in distal conflicts (≥25 years). Data Extraction Methodological factors (response rate, sample size and design, diagnostic method) and substantive factors (sociodemographics, place of survey, torture and other PTEs, Political Terror Scale score, residency status, time since conflict). Data Synthesis A total of 161 articles reporting results of 181 surveys comprising 81 866 refugees and other conflict-affected persons from 40 countries were identified. Rates of reported PTSD and depression showed large intersurvey variability (0%-99% and 3%-85.5%, respectively). The unadjusted weighted prevalence rate reported across all surveys for PTSD was 30.6% (95% CI, 26.3%-35.2%) and for depression was 30.8% (95% CI, 26.3%-35.6%). Methodological factors accounted for 12.9% and 27.7% PTSD and depression, respectively. Nonrandom sampling, small sample sizes, and self-report questionnaires were associated with higher rates of mental disorder. Adjusting for methodological factors, reported torture (Δ total R 2 between base methodological model and base model + substantive factor [ΔR 2 ] = 23.6%; OR, 2.01; 95% CI, 1.52-2.65) emerged as the strongest factor associated with PTSD, followed by cumulative exposure to PTEs (ΔR 2  = 10.8%; OR, 1.52; 95% CI, 1.21-1.91), time since conflict (ΔR 2  = 10%; OR, 0.77; 95% CI, 0.66-0.91), and assessed level of political terror (ΔR 2  = 3.5%; OR, 1.60; 95% CI, 1.03-2.50). For depression, significant factors were number of PTEs (ΔR 2  = 22.0%; OR, 1.64; 95% CI, 1.39-1.93), time since conflict (ΔR 2  = 21.9%; OR, 0.80; 95% CI, 0.69-0.93), reported torture (ΔR 2  = 11.4%; OR, 1.48; 95% CI, 1.07-2.04), and residency status (ΔR 2  = 5.0%; OR, 1.30; 95% CI, 1.07-1.57). Conclusion Methodological factors and substantive population risk factors, such as exposure to torture and other PTEs, after adjusting for methodological factors account for higher rates of reported prevalence of PTSD and depression.

Association of Torture and Other Potentially Traumatic Events With Mental Health Outcomes Among Populations Exposed to Mass Conflict and Displacement: A Systematic Review and Meta-analysis

Since trauma arises from an inescapable stressful event that overwhelms people's coping mechanisms, it is uncertain to what degree the results of laboratory studies of ordinary events are relevant to the understanding of traumatic memories. This paper reviews the literature on differences between recollections of stressful and of traumatic events. It then reviews the evidence implicating dissociation as the central pathogenic mechanism that gives rise to posttraumatic stress disorder (PTSD). A systematic exploratory study of 46 subjects with PTSD indicated that traumatic memories were retrieved, at least initially, in the form of dissociated mental imprints of sensory and affective elements of the traumatic experience: as visual, olfactory, affective, auditory, and kinesthetic experiences. Over time, subjects reported the gradual emergence of a personal narrative that can be properly referred to as “explicit memory.” The implications of these findings for understanding the nature of traumatic memories are discussed.

Dissociation and the fragmentary nature of traumatic memories: Overview and exploratory study

Developmental traumatology part II: brain development ∗

BACKGROUND Research into the mental health of refugees has burgeoned in recent times, but there is a dearth of studies focusing specifically on the factors associated with psychiatric distress in asylum-seekers who have not been accorded residency status.

METHOD Forty consecutive asylum-seekers attending a community resource centre in Sydney, Australia, were interviewed using structured instruments and questionnaires.

RESULTS Anxiety scores were associated with female gender, poverty, and conflict with immigration officials, while loneliness and boredom were linked with both anxiety and depression. Thirty subjects (79%) had experienced a traumatic event such as witnessing killings, being assaulted, or suffering torture and captivity, and 14 subjects (37%) met full criteria for PTSD. A diagnosis of PTSD was associated with greater exposure to pre-migration trauma, delays in processing refugee applications, difficulties in dealing with immigration officials, obstacles to employment, racial discrimination, and loneliness and boredom.

CONCLUSIONS Although based on correlational data derived from'a convenient' sample, our findings raise the possibility that current procedures for dealing with asylum-seekers may contribute to high levels of stress and psychiatric symptoms in those who have been previously traumatised.

Anxiety, depression and PTSD in asylum-seekers: assocations with pre-migration trauma and post-migration stressors.

ContextRefugees experience multiple traumatic events and have significant associated
health problems, but data about refugee trauma and health status are often
conflicting and difficult to interpret.ObjectivesTo assess the characteristics of the literature on refugee trauma and
health, to identify and evaluate instruments used to measure refugee trauma
and health status, and to recommend improvements.Data SourcesMEDLINE, PsychInfo, Health and PsychoSocial Instruments, CINAHL, and
Cochrane Systematic Reviews (searched through OVID from the inception of each
database to October 2001), and the New Mexico Refugee Project database.Study SelectionKey terms and combination operators were applied to identify English-language
publications evaluating measurement of refugee trauma and/or health status.Data ExtractionInformation extracted for each article included author; year of publication;
primary focus; type (empirical, review, or descriptive); and type/name and
properties of instrument(s) included. Articles were excluded from further
analyses if they were review or descriptive, were not primarily about refugee
health status or trauma, or were only about infectious diseases. Instruments
were then evaluated according to 5 criteria (purpose, construct definition,
design, developmental process, reliability and validity) as described in the
published literature.Data SynthesisOf 394 publications identified, 183 were included for further analyses
of their characteristics; 91 (49.7%) included quantitative data but did not
evaluate measurement properties of instruments used in refugee research, 78
(42.6%) reported on statistical relationships between measures (presuming
validity), and 14 (7.7%) were only about statistical properties of instruments.
In these 183 publications, 125 different instruments were used; of these,
12 were developed in refugee research. None of these instruments fully met
all 5 evaluation criteria, 3 met 4 criteria, and 5 met only 1 of the criteria.
Another 8 standard instruments were designed and developed in nonrefugee populations
but adapted for use in refugee research; of these, 2 met all 5 criteria and
6 met 4 criteria.ConclusionsThe majority of articles about refugee trauma or health are either descriptive
or include quantitative data from instruments that have limited or untested
validity and reliability in refugees. Primary limitations to accurate measurement
in refugee research are the lack of theoretical bases to instruments and inattention
to using and reporting sound measurement principles.

https://jamanetwork.com/HttpHandlers/ArticlePdfHandler.ashx?journal=JAMA&articleId=195170&pdfFileName=jrv20018.pdf

Measuring Trauma and Health Status in Refugees: A Critical Review

We present a review of the international literature on the medical and psychological effects of torture. Our review reveals that certain tortures and their physical and emotional sequelae are more prevalent than previously appreciated. They include the common occurrence of sexual violence during the torture of women and female adolescents and the high frequency of head injury and associated neuropsychiatric consequences. We recommend the use of standardized diagnostic criteria in the evaluation of patients who have survived torture; this will facilitate patient care and the documentation of human rights violations. (JAMA1988;259:2725-2729)

https://jamanetwork.com/HttpHandlers/ArticlePdfHandler.ashx?journal=jama&articleId=371911&pdfFileName=jama_259_18_032.pdf

Barbara H. Pesavento

Papers

The Physical and Psychological Sequelae of Torture: Symptomatology and Diagnosis