This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Point-of-care fluidic systems and uses thereof

The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

Integrated health data capture and analysis system

Systems and methods of sample processing and fluid control in a fluidic system

Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples to levels of 1 femtomolar, 1 attomolar, or lower. The methods, kits, and compositions also allow the determination of concentration over a wide range, e.g., 7-log range, without need for sample dilution.

Methods and Compositions for Highly Sensitive Detection of Molecules

Disclosed are methods of identifying subjects with arteriovascular disease, subjects at risk for developing arteriovascular disease, methods of differentially diagnosing diseases associated with arteriovascular disease from other diseases or within sub-classifications of arteriovascular disease, methods of evaluating the risk of arteriovascular events in patients with arteriovascular disease, methods of evaluating the effectiveness of treatments in subjects with arteriovascular disease, and methods of selecting therapies for treating arteriovascular disease.

Markers associated with arteriovascular events and methods of use thereof

The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.

System and methods for sample analysis

The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles of for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.

System and method for spectroscopic analysis of single particles

System und verfahren zur spektroskopischen analyse einzelner partikel

Analyseurs et systemes d'analyse qui comprennent un analyseur de particule unique, methodes d'utilisation desdits analyseurs et desdits systemes d'analyse pour analyser des echantillons, soit pour des particules uniques, soit pour des particules multiples (multiplexage), methodes d'utilisation commerciale desdits analyseurs ou systemes d'analyse et supports electroniques destines a la mise en memoire des parametres utiles dans les analyseurs et systemes d'analyse selon la presente invention.

Barbara Klein

Papers

System and methods for sample analysis

System and method for spectroscopic analysis of single particles

System und verfahren zur spektroskopischen analyse einzelner partikel

Systeme et methode d'analyse d'echantillons