Lignans, neolignans, and related compounds.

Biaryls in nature: a multi-facetted class of stereochemically, biosynthetically, and pharmacologically intriguing secondary metabolites.

Lignans, an amide and anti-platelet activities from Piper philippinum.

Three new arylnaphthalene lignans, namely phyllanthusmins A-C, together with nine known compounds were isolated and characterized from the stems and roots of Phyllanthus oligospermus by a bioassay-guided purification. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Among them, phyllanthusminA displayed significant cytotoxicity against KB and P-388 cancer cell lines.

Cytotoxic arylnaphthalene lignans from Phyllanthus oligospermus.

The genus Bursera belongs to the family Burseraceae and has been used in traditional Mexican medicine for treating various pathophysiological disorders. The most representative phytochemicals isolated from this genus are terpenoids and lignans. Lignans are phenolic metabolites known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, and anti-protozoal properties. Though the genus includes more than 100 species, we have attempted to summarize the biological activities of the 34 lignans isolated from selected Mexican Bursera plants.

https://www.mdpi.com/1420-3049/23/8/1976/pdf

Belkis Gōzler

Papers

Haplomyrtin and (−)-haplomyrfolin: two lignans from haplophyllum myrtifolium