Bernardo Leo Wajchenberg

TL;DR: Methods for assessment of several phenotypes of human obesity, with special reference to abdominal fat content, have been evaluated and the endocrine regulation of abdominal visceral fat in comparison with the adipose tissue localized in other areas is presented.

TL;DR: Among the interventions to preserve or "rejuvenate" beta-cells, short-term intensive insulin therapy of newly diagnosed type 2 diabetes will improve beta-cell function, usually leading to a temporary remission time and the use of antiapoptotic drugs, such as the thiazolidinediones (TZDs), and incretin mimetics and enhancers, which have demonstrated significant clinical evidence of effects on human beta- cell function.

TL;DR: It is concluded that lowering of elevated plasma FFA levels can reduce insulin resistance/hyperinsulinemia and improve oral glucose tolerance in lean and obese nondiabetic subjects and in obese patients with type 2 diabetes.

TL;DR: The clinical features and natural history of adrenocortical carcinoma are highly dependent on the type of center reporting their experience, whereas reports from endocrine clinics emphasize excessive corticoid and androgen production in the majority of tumors.

TL;DR: In this article, the authors evaluated the relationship between VAT and components of the metabolic syndrome and found that VAT contributes more to insulin resistance (HOMA IR) than SAT does, but not when insulin-suppressed plasma free fatty acids during oral glucose tolerance test as an index of insulin resistance are taken into consideration.