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Bo Song
Researcher at Dalian Medical University
Publications - 58
Citations - 2931
Bo Song is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Cell growth & Cancer. The author has an hindex of 26, co-authored 56 publications receiving 2565 citations. Previous affiliations of Bo Song include Stony Brook University & Yale University.
Papers
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Journal ArticleDOI
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
Bo Song,Yuan Wang,Yuan Wang,Yaguang Xi,Kenji Kudo,Skjalg Bruheim,Galina I. Botchkina,Elaine Gavin,Yu Wan,Andrea Formentini,Marko Kornmann,Øystein Fodstad,Jingfang Ju +12 more
TL;DR: Findings indicate that miR-140 is involved in the chemoresistance by reduced cell proliferation through G1 and G2 phase arrest mediated in part through the suppression of HDAC4.
Journal ArticleDOI
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells
Bo Song,Yuan Wang,Yuan Wang,Matthew A. Titmus,Galina I. Botchkina,Andrea Formentini,Marko Kornmann,Jingfang Ju +7 more
TL;DR: It is indicated that miR-215, through the suppression of DTL expression, induces a decreased cell proliferation by causing G2-arrest, thereby leading to an increase in chemoresistance to MTX and TDX.
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Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment.
Jiakai Mao,Shujun Fan,Wei Ma,Panhong Fan,Bo Wang,Junlin Zhang,Honghai Wang,Bo Tang,Qingqing Zhang,Xiaotang Yu,Lihui Wang,Bo Song,Lianhong Li +12 more
TL;DR: It is suggested that Wnt signaling might have a critical role in the self-renewal of gastric CSCs, and salinomycin targeting WNT signaling may have important clinical applications in gastric cancer therapy.
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Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation.
Elizabeth Louie,Sara Nik,Juei-suei Chen,Marlies Schmidt,Bo Song,Christine Pacson,Xiu Fang Chen,Seonhye Park,Jingfang Ju,Emily I. Chen +9 more
TL;DR: These results provide the validity to the newly developed hypoxia/reoxygenation culture system for examining the regulation of CSCs in breast cancer cell lines by niche factors in the tumor microenvironment and developing differential targeting strategies to eradicate breast C SCs.
Journal ArticleDOI
miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit.
TL;DR: The results indicate that miR-192 may be another miRNA candidate that is involved in the p53 tumor suppressor network with significant effect on cell cycle control and cell proliferation.