Buck S. Samuel

TL;DR: Using metabolic function analyses of identified genes, the human genome is compared with the average content of previously sequenced microbial genomes and humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes.

TL;DR: Functional genomic, biochemical, and physiologic studies reveal that Gpr41 is a regulator of host energy balance through effects that are dependent upon the gut microbiota.

TL;DR: Methods for producing and rearing germ-free zebrafish through late juvenile stages are developed and established as a useful model for dissecting the molecular foundations of host-microbial interactions in the vertebrate digestive tract.

TL;DR: A link between this archaeon, prioritized bacterial utilization of polysaccharides commonly encountered in the authors' modern diets, and host energy balance is demonstrated and demonstrate a link between B. thetaiotaomicron and the contributions of Archaea to digestive health.

TL;DR: Results indicate that M. smithii is well equipped to persist in the distal intestine through production of surface glycans resembling those found in the gut mucosa, and regulated expression of adhesin-like proteins, and consumption of a variety of fermentation products produced by saccharolytic bacteria, and effective competition for nitrogenous nutrient pools.