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Caixia Xia
Researcher at Zhejiang University
Publications - 17
Citations - 287
Caixia Xia is an academic researcher from Zhejiang University. The author has contributed to research in topics: Hepatitis B & Cirrhosis. The author has an hindex of 6, co-authored 14 publications receiving 155 citations. Previous affiliations of Caixia Xia include Nanjing Medical University.
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Journal ArticleDOI
MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
Guohua Lou,Liang Chen,Caixia Xia,Weina Wang,Jinjin Qi,Aichun Li,Liying Zhao,Zhi Chen,Min Zheng,Yanning Liu +9 more
TL;DR: AMSC-Exo- 199a can be an effective vehicle for miR-199a delivery, and they effectively sensitized HCC to chemotherapeutic agents by targeting mTOR pathway and subsequently inhibiting the m TOR pathway.
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Involvement of Interleukin 6 in Hepatitis B Viral Infection.
TL;DR: This review aims to present the latest discoveries concerning the role of IL-6 in hepatitis B disease progression, and HBV entry and replication, and evaluate polymorphisms that are associated with the development of hepatitis B Disease.
Journal ArticleDOI
Direct targeting sperm-associated antigen 9 by miR-141 influences hepatocellular carcinoma cell growth and metastasis via JNK pathway.
Guohua Lou,Xuejun Dong,Caixia Xia,Bingjue Ye,Qiuyue Yan,Shanshan Wu,Ye Yu,Feifei Liu,Min Zheng,Zhi Chen,Yanning Liu +10 more
TL;DR: MiR-141 suppression may cause aberrant expression of SPAG9 and promote HCC tumorigenesis via JNK pathway and dual-luciferase reporter assay showed that SPAg9 was a direct target gene of miR- 141.
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Isoliquiritigenin Inhibits Interferon-γ-Inducible Genes Expression in Hepatocytes through Down-Regulating Activation of JAK1/STAT1, IRF3/MyD88, ERK/MAPK, JNK/MAPK and PI3K/Akt Signaling Pathways.
Shanshan Wu,Jihua Xue,Ying Yang,Hai-Hong Zhu,Feng Chen,Jing Wang,Guohua Lou,Yanning Liu,Yixian Shi,Ye Yu,Caixia Xia,Ying Hu,Zhi Chen +12 more
TL;DR: It is demonstrated that ISL inhibits IFN-γ-induced inflammation in hepatocytes via influencing the activation of JAK1/STAT1, IRF3/MyD88, ERK/ MAPK, JNK/MAPK, and PI3K/Akt signaling pathways.
Journal ArticleDOI
0404 inhibits hepatocellular carcinoma through a p53/miR-34a/SIRT1 positive feedback loop.
Caixia Xia,Caixia Xia,Liyan Shui,Guohua Lou,Bingjue Ye,Zhu Wei,Jing Wang,Shanshan Wu,Xiao Xu,Long Mao,Wanhong Xu,Zhi Chen,Yanning Liu,Min Zheng +13 more
TL;DR: The findings show that 0404 is probably an attractive agent for treating HCC, especially in HCC with wide type (WT) p53, through forming a p53/miR-34a/SIRT1 signal feedback loop to promote cell apoptosis.