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Camilla M. Kao
Researcher at Stanford University
Publications - 53
Citations - 7502
Camilla M. Kao is an academic researcher from Stanford University. The author has contributed to research in topics: Polyketide & Polyketide synthase. The author has an hindex of 25, co-authored 53 publications receiving 7228 citations. Previous affiliations of Camilla M. Kao include Brown University.
Papers
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Journal ArticleDOI
Genomic expression programs in the response of yeast cells to environmental changes.
Audrey P. Gasch,Paul T. Spellman,Camilla M. Kao,Orna Carmel-Harel,Michael B. Eisen,Gisela Storz,David Botstein,Patrick O. Brown +7 more
TL;DR: Analysis of genomic expression patterns in the yeast Saccharomyces cerevisiae implicated the transcription factors Yap1p, as well as Msn2p and Msn4p, in mediating specific features of the transcriptional response, while the identification of novel sequence elements provided clues to novel regulators.
Journal ArticleDOI
Engineered biosynthesis of a complete macrolactone in a heterologous host
TL;DR: The biosynthetic strategy utilizes a genetic approach that facilitates rapid structural manipulation of DEBS or other modular polyketide synthases (PKSs), including those found in actinomycetes with poorly developed genetic methods.
Journal ArticleDOI
The chaplins: a family of hydrophobic cell-surface proteins involved in aerial mycelium formation in Streptomyces coelicolor
Marie A. Elliot,Nitsara Karoonuthaisiri,Jianqiang Huang,Maureen J. Bibb,Stanley N. Cohen,Camilla M. Kao,Mark J. Buttner +6 more
TL;DR: Observations implicate the chaplin genes in aerial mycelium formation, and suggest that coating of the envelope by the chaplins is required for aerial hyphae to grow out of the aqueous environment of the substrateMycelium into the air.
Journal ArticleDOI
Cross‐regulation among disparate antibiotic biosynthetic pathways of Streptomyces coelicolor
Jianqiang Huang,Jing Shi,Virginie Molle,Björn Sohlberg,David Weaver,Maureen J. Bibb,Nitsara Karoonuthaisiri,Chih-Jian Lih,Camilla M. Kao,Mark J. Buttner,Stanley N. Cohen +10 more
TL;DR: A network of functional interactions among regulators that govern production of antibiotics and other secondary metabolites in S. coelicolor are revealed, which suggest that revision of the currently prevalent view of higher‐level versus pathway‐specific regulation of secondary metabolism in Streptomyces species is warranted.
Patent
Recombinant production of novel polyketides
TL;DR: In this paper, a host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.