C
Canzhan Zhu
Researcher at Xi'an Jiaotong University
Publications - 4
Citations - 20
Canzhan Zhu is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: ABCG1 & Downregulation and upregulation. The author has an hindex of 2, co-authored 4 publications receiving 19 citations.
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Journal ArticleDOI
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway
TL;DR: It is suggested that reduction of ABCG1 induces endothelial apoptosis, which seems associated with intracellular free cholesterol accumulation and subsequent ER stress.
Journal ArticleDOI
ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose
TL;DR: It is suggested that ABCG1 plays an important role in protecting against endothelial dysfunction induced by high glucose, and high glucose suppressedABCG1 expression and intracellular cholesterol efflux to HDL.
Journal Article
[Endothelial dysfunction induced by high glucose is associated with decreased ATP-binding cassette transporter G1 expression].
TL;DR: Endothelial dysfunction induced by high glucose is associated with decreased ABCG1 expression and cholesterol efflux to HDL in HAECs, which was abolished by treatment of the cells with the LXR agonist.
Journal ArticleDOI
GW28-e1203 ABCG1 attenuates Oxidative Stress Induced by TNF-α through the inhibition of NADPH oxidase and the upregulation of antioxidant enzymes in endothelial cells
TL;DR: In this article, the ATP-binding cassette transporter G1 (ABCG1), a regulator of cellular lipid metabolism, has been found to reverse the high glucose-induced oxidative stress in previous studies.