Carlo M. Croce

TL;DR: Data indicate that PO and PS oligodeoxynucleotides targeted against the human BCL2 protooncogene can be sequence-specific inhibitors of leukemic cell growth and survival.

TL;DR: The cloning and the characterization of the partner gene from chromosome 6 (AF-6), which is expressed in a variety of cell types and encodes a protein of 1612 amino acids, contains the GLGF motif shared with several proteins of vertebrates and invertebrates thought to be involved in signal transduction at special cell-cell junctions.

TL;DR: Two new members (elk-1 and elk-2) of the ets oncogene superfamily have now been identified and the possibility that rearrangements of elk loci may be involved in pathogenesis of certain tumors is suggested.

TL;DR: The ability of the translocated c-myc oncogene to escape the normal transcriptional control occurring in B cells may be important for the expression of B cell neoplasia in mouse and man.

TL;DR: Analysis of sequence comparisons among LCA, the LCA-related protein LAR, and RPTPase alpha, beta, and gamma reveals the existence of a multigene family encoding different RPTPases, each containing a distinct extracellular domain, a single hydrophobic transmembrane region, and two tandemly repeated conserved cytoplasmic domains.