C
Carlos Juarez
Researcher at University of Manitoba
Publications - 43
Citations - 2798
Carlos Juarez is an academic researcher from University of Manitoba. The author has contributed to research in topics: Penicillin & Radioallergosorbent test. The author has an hindex of 26, co-authored 43 publications receiving 2681 citations.
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Journal ArticleDOI
Natural evolution of skin test sensitivity in patients allergic to β- lactam antibiotics
Miguel Blanca,María José Torres,Juan Jesus García,Antonino Romano,Cristobalina Mayorga,Enrique de Ramon,J. M. Vega,A. Miranda,Carlos Juarez +8 more
TL;DR: Patients with a selective response to amoxicillin tended to lose sensitivity faster than those who responded to several penicillin determinants, supporting the existence of at least 2 distinct types of IgE response in patients allergic to beta-lactam.
Journal ArticleDOI
Diagnostic evaluation of a large group of patients with immediate allergy to penicillins: the role of skin testing.
J. Torres,Antonino Romano,Cristobalina Mayorga,M. Carmen,Antonio E. Guzmán,M. Reche,Carlos Juarez,Miguel Blanca +7 more
TL;DR: The diagnostic value of skin testing in penicillin‐allergic subjects from a population where benzylpenicillin is not now the most frequently used β‐lactam is studied.
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Delayed reactions to drugs show levels of perforin, granzyme B, and Fas-L to be related to disease severity
S Posadas,A. Padial,María José Torres,Cristobalina Mayorga,Laura Leyva,Elena Sanchez,J. Alvarez,Antonino Romano,Carlos Juarez,Miguel Blanca +9 more
TL;DR: The data show that TNF-alpha, perforin, GrB, and FasL are increased in the early stage of disease, suggesting that a cytotoxic mechanism might be taking part, support the role of T cells in allergic drug reactions and provide further clues pertaining to therapeutic interventions.
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Clinical evaluation of Pharmacia CAP System RAST FEIA amoxicilloyl and benzylpenicilloyl in patients with penicillin allergy.
Miguel Blanca,Cristobalina Mayorga,María José Torres,M. Reche,MC Moya,J. Rodriguez,Antonino Romano,Carlos Juarez +7 more
TL;DR: The objective was to evaluate the diagnostic capacity of Pharmacia CAP System™ RAST FEIA amoxicilloyl c6 (AXO) and benzylpenicilloysl c1 (BPO) in patients with a documented IgE‐mediated penicillin allergy.
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Allergy to penicillin with good tolerance to other penicillins; study of the incidence in subjects allergic to betalactams
Miguel Blanca,J. M. Vega,J. Garcia,M.J. Carmona,S. Terados,Maria J. Avila,A. Miranda,Carlos Juarez +7 more
TL;DR: The challenge tests suggested that not all the penicillin‐sensitive subjects had IgE‐mediated reactions implying other immunological mechanisms, demonstrating the importance of side chain‐specific diagnostic reagents and challenge tests.