Showing papers by "Carrie L. Byington published in 1998"
TL;DR: The costs of a sepsis evaluation outweigh the benefits in infants with obvious bronchiolitis; the risk of serious bacterial infection is low; the costs of the decision and the clinical and cost outcomes are low.
Abstract: Objectives.To define variation in the decision to perform a sepsis evaluation in hospitalized infants with bronchiolitis, to define predictors of the decision and to measure the clinical and cost outcomes.Methods.Retrospective chart review of all non-intensive care unit infants ≤60 days with any
92 citations
TL;DR: The incorporation of a commercially available coprecipitant into the AMPLICOR enterovirus PCR test specimen preparation enhanced the sensitivity and reproducibility of this assay and support the utility of a coprecIPitant in minimizing false-negative results.
Abstract: The incorporation of a commercially available coprecipitant into the AMPLICOR enterovirus PCR test specimen preparation enhanced the sensitivity and reproducibility of this assay. Fifty-five previously tested archived cerebrospinal fluids (CSF) specimens were tested in a blind study in duplicate with and without Pellet Paint coprecipitant (Novagen, Inc., Madison, Wis.). Of these specimens, 26 had previously been determined to be positive and 29 had previously been determined to be negative. All previously positive CSF specimens were positive when Pellet Paint was used and only 18 were positive without Pellet Paint. No previously negative specimens were positive on repeat testing with or without Pellet Paint. The background signal was not affected by the addition of Pellet Paint. These data support the utility of a coprecipitant in minimizing false-negative results.
11 citations
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