The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

Inhibitors of histone deacetylase

This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).

Il-8 receptor antagonists

Omega-carboxyaryl substituted diphenyl ureas are disclosed which are useful as raf kinase inhibitors. This disclosure also relates to the use of a group of these aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.

Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors

This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.

Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas

This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.

OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS

N-hydroxyphenyl-N'-phenylureas useful as active ingredients in preparations for combatting harmful micro-organisms, especially bacteria.

Casagrande Dr Fulvio

Papers

N-hydroxyphenyl-n{40 -phenylureas

N-Hydroxyphenyl-N'-phenylharnstoffe,ihre Herstellung und Verwendung