C
Cathy Clarke
Publications - 2
Citations - 1217
Cathy Clarke is an academic researcher. The author has contributed to research in topics: Vorinostat & Histone deacetylase. The author has an hindex of 2, co-authored 2 publications receiving 1147 citations.
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Journal ArticleDOI
Histone Deacetylase Inhibitors: Overview and Perspectives
TL;DR: This review focuses on the activities of the 11 zinc-containing HDACs, their histone and nonhistone protein substrates, and the different pathways by which HDACi induce transformed cell death.
Journal ArticleDOI
Histone deacetylase inhibitors selectively suppress expression of HDAC7
Milos Dokmanovic,G. Perez,Weisheng Xu,Lang Ngo,Cathy Clarke,Raphael B. Parmigiani,Paul A. Marks +6 more
TL;DR: It is found that vorinostat selectively down-regulates HDAC7 with little or no effect on the expression of other class I or class II HDACs, which may serve as a marker of response of tumors to HDACi.