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Chandra Inglis
Researcher at Torrey Pines Institute for Molecular Studies
Publications - 4
Citations - 162
Chandra Inglis is an academic researcher from Torrey Pines Institute for Molecular Studies. The author has contributed to research in topics: Chemokine receptor & Cytotoxic T cell. The author has an hindex of 3, co-authored 4 publications receiving 154 citations.
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Journal ArticleDOI
CXCR2 Is Required for Neutrophil Recruitment to the Lung during Influenza Virus Infection, But Is Not Essential for Viral Clearance
TL;DR: It appears that CXCR2 is the major receptor mediating neutrophil trafficking to the lung during influenza virus infection, but that neutrophils do not play an essential role in viral clearance.
Journal ArticleDOI
Chemokine regulation of the inflammatory response to a low-dose influenza infection in CCR2–/– mice
Mark D. Wareing,Ashley B. Lyon,Chandra Inglis,Francesca Giannoni,Israel F. Charo,Sally R. Sarawar +5 more
TL;DR: It is shown that low‐dose influenza infection of CCR2−/− mice leads to increased neutrophilia between Days 5 and 10 after infection and decreased monocyte/macrophage and CD4+ T cell recruitment to the lungs between days 5 and 7 after infection, which suggest that CCR1 plays a multifactorial role in the development of the immune response to influenza.
Journal ArticleDOI
CD40 Engagement on Dendritic Cells, but Not on B or T Cells, Is Required for Long-Term Control of Murine Gammaherpesvirus 68
TL;DR: The data suggest that CD40 engagement on DC, but not on T or B cells, is essential for effective long-term control of MHV-68, and the results showed thatCD40 expression on T cells is not necessary for preventing viral reactivation.
Journal ArticleDOI
Primary Clearance of Murine Gammaherpesvirus 68 by PKCθ−/− CD8 T Cells Is Compromised in the Absence of Help from CD4 T Cells
TL;DR: It is found that while either CD4 or CD8 T cells could mediate the clearance of MHV-68 from the lungs of PKC θ+/+ mice, PKCθ−/− mice depleted of either subset failed to clear the virus.