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Chao Jian
Researcher at Fourth Military Medical University
Publications - 2
Citations - 44
Chao Jian is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Downregulation and upregulation & Receptor. The author has an hindex of 2, co-authored 2 publications receiving 33 citations.
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Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer.
Zhijie Lei,Na Chai,Miaomiao Tian,Ying Zhang,Guodong Wang,Jian Liu,Zuhong Tian,Xiaofang Yi,Di Chen,Xiaowei Li,Pengfei Yu,Hao Hu,Bing Xu,Chao Jian,Zhenyuan Bian,Hao Guo,Jinpeng Wang,Shiming Peng,Yongzhan Nie,Niu Huang,Sijun Hu,Kaichun Wu +21 more
TL;DR: It is observed that GX1 could inhibit the GTP-binding activity of TGM2 by reducing its intracellular distribution and downregulating its downstream molecular targets (nuclear factor-kappa B, NF-κB; hypoxia-inducible factor 1-α, HIF1α) in GC vascular endothelial cells.
Journal ArticleDOI
New Generation of Gold Nanoshell-Coated Esophageal Stent: Preparation and Biomedical Applications
TL;DR: Compared with bare metal stent, AuNS-modified stent exhibits great potential to open the duct passageway and suppress tumor growth in future clinical applications and in vitro toxicity experiments showed excellent biocompatibility and safety of this device.