Bioactive compounds from medicinal plants: Focus on Piper species

Ethno pharmacological relevance: Traditional medicinal plants are practiced worldwide for treatment of arthritis especially in developing countries where resources are meagre. This review presents the plants profiles inhabiting throughout the world regarding their traditional usage by various tribes/ethnic groups for treatment of arthritis.
Materials and methods: Bibliographic investigation was carried out by analysing classical text books and peer reviewed papers, consulting worldwide accepted scientific databases from the last six decades. Plants/their parts/extracts/polyherbal formulations/toxicity studies for arthritis have been included in the review article. The profiles presented also include information about the scientific name, family, dose, methodology along with mechanism of action and toxicity profile. Research status of twenty potential plant species has been discussed. Further, geographical distribution of research, plants distribution according to families has been given in graphical form.
Results: 485 plant species belonging to 100 families, traditionally used in arthritis are used. Among 100 plant families, malvaceae constitute 16, leguminasae 7, fabaceae 13, euphorbiaceae 7, compositae 20, araceae 7, solanaceae 12, liliaceae 9, apocynaceae, lauraceae and rubiaceae 10, and remaining in lesser proportion. It was observed in our study that majority of researches are carried mainly in developing countries like India, China, Korea and Nigeria.
Conclusion: This review clearly indicates that list of medicinal plants presented in this review might be useful to researchers as well as practioners. This review can be useful for preliminary screening of potential anti- arthritis plants. Further toxicity profile given in the review can be useful for the researchers for finding the safe dose.

Medicinal plants with potential anti-arthritic activity:

Ocular toxicity of ethambutol

A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research

Optic neuritis and its differential diagnosis

Medicinal plants have shown tremendous potential for the development of the new drug molecules for various serious diseases. Many plant derived products have found to play an important role in various disease conditions. Piper longum Linn. is a native of the Indo-Malaya region, belongs to family Piperaceae. Piper longum Linn. (Piperaceae) has been used as a therapeutic agent in the treatment of various pathological conditions. The tribal population uses the plant for cardiovascular activities, anti-inflammatory activity and as a spice. Alkaloids, Lignans and volatile oil are reported in this plant. Extract of Piper longum fruits have been shown to posses various activities like Bio-availibity enhancer, immunomodulatory effect, antiasthamatic and hepatoprotective activity. In the present review an attempt has been made to explore different aspects of Piper longum.

Phytoc hemical and therapeutic potential of piper longum linn a review

Paederia foetida Linn. as a potential medicinal plant: a review.

Optic neuritis is a serious condition which typically involves the young adult population. Years ago it was thought that one third of optic neuritis patients would go on to have neurological symptoms from multiple sclerosi s (MS). More recent studies show its association with vaccination & ethambutol treatment in tuberculosis. The present article is alert to the symptoms of optic neuritis, its diagnostic criteria , association with various serious diseases and some herbal tre atment to counteract associated symptoms.

Chauhan Khushbu

Papers

Phytoc hemical and therapeutic potential of piper longum linn a review

Paederia foetida Linn. as a potential medicinal plant: a review.

An overview on optic neuritis