Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63.

Terpenes are one of the most abundant classes of secondary metabolites produced by plants and can be divided based on the number of isoprene units (C5) in monoterpenes (2 units—C10), sesquiterpenes (3 units—C15), diterpenes (4 units—C20), triterpenes (6 units—C30), etc. Chemically, triterpenes are classified based on their structural skeleton including lanostanes, euphanes, cycloartanes, ursanes, oleananes, lupanes, tirucallanes, cucurbitanes, dammaranes, baccharanes, friedelanes, hopanes, serratanes etc. Additionally, glycosylated (saponins) or highly oxidated/degraded (limonoids) triterpenes could be found in nature. The antiinflammatory effect and action as immunomodulators of these secondary metabolites have been demonstrated in different studies. This review reports an overview of articles published in the last 15 years (from 2006 to 2021 using PubMed and SciFinder database) describing the antiinflammatory effects of different triterpenes with their presumed mechanism of action, suggesting that triterpenes could be appointed as natural products with future pharmaceutical applicability.

Antiinflammatory activity of natural triterpenes—An overview from 2006 to 2021

A new supramolecular natural product gel based on self-assembled pomolic acid from traditional Chinese medicine

Ethnobotany, phytochemistry, pharmacology, and toxicology of the genus sambucus L. (Viburnaceae).

Chemical components from Sambucus adnata wall

Bioactive triterpenoids from Sambucus javanica Blume.

The invention discloses a sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and a preparation method thereof, and relates to the technical field of application of natural plant extract in the field of medicine. The sambucus adnata hard ointment capable of diminishing inflammation and relieving pain is prepared from, by mass, 1-30% of sambucus adnata extract, 1-30% of fatty acid alkali metal salt, 10-80% of monohydric alcohol, 0.5-50% of polyhydric alcohol, 2-10% of an auxiliary material and 15-40% of aids. The hard ointment is mainly used for treating traumatic injuries, sprains and mild water or fire scalds, is definite in treatment effect, prolongs the action time of active ingredients on affected parts and increases the utilization rate of active ingredients on affected parts, and the action effect of medicine is enhanced; besides, the preparation method of the hard ointment is simple and has the advantages that temperature control is easy, grinding is not needed, the character is good and preparation is easy, and the preparation method is especially suitable for large-scale industrial production.

Sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and preparation method thereof

The invention discloses a preparation method of a Herba Sambuci Adnatae extract and an application thereof in rheumatoid arthritis, and relates to the technical field of a plant extract, and a preparation method and an application thereof. The preparation method comprises the following steps: after pulverizing Herba Sambuci Adnatae, adding 5-10 times of a solvent; repeatedly extracting for 4 times at the temperature of 35-100 DEG C; and then heating a concentrated solution and carrying out freeze drying to obtain the Herba Sambuci Adnatae extract. The prepared Herba Sambuci Adnatae extract is used for treating rat rheumatoid arthritis induced by II type collagen, and the result shows that the Herba Sambuci Adnatae extract can remarkably improve level of rat foot swelling caused by the rheumatoid arthritis induced by a freund's adjuvant, the IL-6 level of a skin reaction factor in serum can be reduced remarkably, and the food intake of a rat is not affected.

Preparation method of Herba Sambuci Adnatae extract and application thereof in rheumatoid arthritis

The invention relates to the fields of natural plant extraction and medicine application, in particular to an external use type adnate elder herb ointment for treating impact injuries and sprains and a preparing method thereof. The external use type adnate elder herb ointment is prepared from, by mass, 0.5-25 wt% of adnate elder herb extract and the balance matrix components. The external use type adnate elder herb ointment is safe and convenient to use and carry, definite in effect and easy to prepare.

Chen Feilong

Papers

Bioactive triterpenoids from Sambucus javanica Blume.

Sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and preparation method thereof

Preparation method of Herba Sambuci Adnatae extract and application thereof in rheumatoid arthritis

External use type adnate elder herb ointment for treating impact injuries and sprains and preparing method thereof