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Chih-Li Lin

Researcher at Chung Shan Medical University

Publications -  70
Citations -  2314

Chih-Li Lin is an academic researcher from Chung Shan Medical University. The author has contributed to research in topics: Insulin resistance & Insulin receptor. The author has an hindex of 22, co-authored 61 publications receiving 1919 citations. Previous affiliations of Chih-Li Lin include National Taiwan University & Taipei Medical University.

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Survey of Catechins, Gallic Acid, and Methylxanthines in Green, Oolong, Pu-erh, and Black Teas

TL;DR: In this paper, an isocratic HPLC procedure was developed for simultaneous determination of six catechins, gallic acid, and three methylxanthines in tea water extract, achieving a baseline separation on a Cosmosil C18-MS packed column with a solvent mixture of methanol/doubly distilled water/formic acid (19.5:80.2:0.3, v/v/v) as mobile phase.
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Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells.

TL;DR: The results show that theaflavins are bioavailable both in vitro and in vivo and may be active in the prevention of fatty liver and obesity and support the idea that AMPK is a critical component of decreased hepatic lipid accumulation by theAFlavin treatments.
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Determination of theanine, GABA, and other amino acids in green, oolong, black, and Pu-erh teas with dabsylation and high-performance liquid chromatography

TL;DR: Analysis of the free amino acid contents of theanine and GABA in different teas with a dabsylation and reverse phase high-performance liquid chromatography (HPLC) system coupled with a detector at 425 nm absorbance suggests that the tea source or the steps of tea-making may contribute to theTheanine contents variations.
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Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice.

TL;DR: It is demonstrated that combination treatment with EGCG and dacarbazine strongly inhibits melanoma growth and metastasis, and the action mechanisms of E GCG are associated with the inhibition of cell spreading, cell‐extracellular matrix and cell‐cell interactions, MMP‐9 and FAK activities.
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Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells.

TL;DR: The data suggest a putative link between high glucose and insulin resistance in HepG2 cells, and the EGCG treatment attenuates insulin signaling blockade by reducing IRS-1 Ser307 phosphorylation through the AMPK activation pathway.