Chris Boesch

TL;DR: It is suggested that AA normal-weight adolescents are not more susceptible than Caucasians to FFA-induced IMCL accumulation and insulin resistance, and reductions in insulin sensitivity with no race differential.

TL;DR: A method for absolute quantitation of in vivo (31)P MR spectra that provides reproducible metabolite contents in institutional or standard units is described that relies on the reciprocity principle, i.e., the proportionality between the B(1) field map and the map of reception strength for a coil with identical relative current distributions in receive and transmit mode.

TL;DR: A recently validated 1H MRS method was used to compare the compositional saturation index and concentration independent of the composition (CH3) of IMCLs in the soleus and tibialis anterior muscles of 16 female insulin-resistant lipodystrophic subjects with that of age- and gender-matched athletes and healthy controls.

TL;DR: The proposed method was modified with adiabatic pulse cycles and the practical use of the proposed method is illustrated with the determination of 31P NMR saturation factors in human calf muscle.

TL;DR: It was demonstrated that detection and monitoring of brain Phe concentrations is feasible by means of 1H MRS, and this approach constitutes a prerequisite for describing carrier kinetics in health.