C
Christian Cavé
Researcher at Université Paris-Saclay
Publications - 83
Citations - 794
Christian Cavé is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Michael reaction & Imine. The author has an hindex of 13, co-authored 82 publications receiving 729 citations. Previous affiliations of Christian Cavé include University of Paris & Centre national de la recherche scientifique.
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A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents
TL;DR: The aim of this review is to update current knowledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities.
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New polymer-supported catalysts derived from cinchona alkaloids : their use in the asymmetric michael reaction
TL;DR: In this paper, new polymer-supported catalysts derived from quinine and quinidine were elaborated and tested in the conjugate addition between enamino ester 13 and methyl vinyl ketone.
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Stereochemical Aspects in the Asymmetric Michael Addition of Chiral Imines to Substituted Electrophilic Alkenes
TL;DR: The Michael-type addition of chiral imines, derived from racemic alpha-substituted cyclanones and optically active 1-phenylethylamine, to electrophilic alkenes, in neutral conditions, constitutes one of the most efficient methods for the stereocontrolled construction of quaternary carbon centers.
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Synthesis of Ursolic Phosphonate Derivatives as Potential Anti-HIV Agents
TL;DR: The preliminary bioassays indicate that synthesized compounds 7a–j have anti-HIV activity (targeting HIV-1 gp120 and CD4) and no cytotoxicity on HT-29 cells (human colon adenocarcinoma cell line).
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Racemization processes at a quaternary carbon center in the context of the asymmetric Michael reaction
Kimny Tan,Rosana Alvarez,Mohammed Nour,Christian Cavé,Angèle Chiaroni,Claude Riche,Jean d'Angelo +6 more
TL;DR: Several examples of racemization process at a quaternary carbon center affecting Michael adducts were reported in this paper, and a brief statement to prevent the occurrence of the interfering retro-Michael reaction was also presented.