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Christian Rainer Wirtz
Researcher at Heidelberg University
Publications - 81
Citations - 2191
Christian Rainer Wirtz is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Intraoperative MRI. The author has an hindex of 22, co-authored 67 publications receiving 1897 citations. Previous affiliations of Christian Rainer Wirtz include University of Ulm.
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Journal ArticleDOI
Clinical evaluation and follow-up results for intraoperative magnetic resonance imaging in neurosurgery.
Christian Rainer Wirtz,Michael Knauth,Andreas Staubert,Matteo M. Bonsanto,Klaus Sartor,Stefan Kunze,Volker M. Tronnier +6 more
TL;DR: Intraoperative MRI is safe and allows reliable updating of neuronavigational data, with compensation for brain shifting, and patients seemed to benefit from the method.
Journal Article
Intraoperative MR imaging increases the extent of tumor resection in patients with high-grade gliomas.
Michael Knauth,Christian Rainer Wirtz,Volker M. Tronnier,Nurdagül Aras,Stefan Kunze,Klaus Sartor +5 more
TL;DR: Intraoperative MR imaging significantly increases the rate of complete tumor removal, which suggests the benefits of intraoperative imaging.
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Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours.
Marc-Eric Halatsch,Ursula Schmidt,Julianne Behnke-Mursch,Andreas Unterberg,Christian Rainer Wirtz +4 more
TL;DR: The HER1/EGFR tyrosine kinase inhibitors erlotinib and gefitinib are in advanced clinical development for glioma, and a number of trials are in progress, or have recently been completed.
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Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients
Rezvan Ahmadi,Christine Dictus,Christian Hartmann,Olga Zürn,Lutz Edler,Marius Hartmann,Stephanie E. Combs,Christel Herold-Mende,Christian Rainer Wirtz,Andreas Unterberg +9 more
TL;DR: Extent of the resection was evaluated in correlation to the overall survival (OS) and progression-free survival (PFS) using Cox regression multivariate analysis and showed that extended surgery would be the most effective therapy for low-grade glioma patients even in recurrent diseases.
Journal ArticleDOI
Tumor detection with 5-aminolevulinic acid fluorescence and Gd-DTPA–enhanced intraoperative MRI at the border of contrast-enhancing lesions: a prospective study based on histopathological assessment
Jan Coburger,Jens Engelke,Angelika Scheuerle,Dietmar Rudolf Thal,Michal Hlavac,Christian Rainer Wirtz,Ralph König +6 more
TL;DR: Evaluated whether 5-aminolevulinic acid (5-ALA) fluorescence provides an additional benefit in detection of invasive tumor compared with intraoperative MRI (iMRI) and in METs, the authors found no additional benefit of 5- ALA compared with iMRI.