C
Christine L. Miller
Researcher at Johns Hopkins University School of Medicine
Publications - 2
Citations - 97
Christine L. Miller is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: RNA extraction & Bipolar disorder. The author has an hindex of 2, co-authored 2 publications receiving 92 citations.
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Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder
TL;DR: Analysis of major pre- and post-mortem variables showed that none were confounding for these between-group experimental comparisons, and known regulators of one of the key kynurenine-producing enzymes, tryptophan 2,3-dioxygenase (TDO2), were investigated.
Journal ArticleDOI
Methods to optimize the generation of cDNA from postmortem human brain tissue.
TL;DR: Evaluating the RT-PCR results per wet weight of tissue extracted, it was found that the signal strength was increased >20-fold by a protocol of Qiagen RNeasy column extraction, random hexamer RT priming and omitting DNase treatment of the RNA.