C
Christine Stephan
Researcher at University of Pittsburgh
Publications - 1
Citations - 327
Christine Stephan is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: P70-S6 Kinase 1. The author has an hindex of 1, co-authored 1 publications receiving 324 citations.
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Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells
Anne Boulay,Sabine Zumstein-Mecker,Christine Stephan,Iwan Beuvink,Frederic Zilbermann,Roland Haller,Sonja Tobler,Christoph Heusser,Terence O'reilly,Barbara Stolz,Andreas Marti,George Thomas,Heidi Lane +12 more
TL;DR: A correlation between the antitumor efficacy of intermittent RAD001 treatment schedules and prolonged S6K1 inactivation in PBMCs is demonstrated and suggest that long-term monitoring of PBMC-derived S 6K1 activity levels could be used for assessing RAD001treatment schedules in cancer patients.