C
Christopher J. Murphy
Researcher at University of California, Davis
Publications - 411
Citations - 18333
Christopher J. Murphy is an academic researcher from University of California, Davis. The author has contributed to research in topics: Cornea & Extracellular matrix. The author has an hindex of 62, co-authored 401 publications receiving 16637 citations. Previous affiliations of Christopher J. Murphy include University College Dublin & Vision-Sciences, Inc..
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Effects of synthetic micro- and nano-structured surfaces on cell behavior
TL;DR: The fabrication of synthetic micro- and nano-structured surfaces and the effects of such textured surfaces on cell behavior are reviewed and the hypothesis that the topography of the basement membrane plays an important role in regulating cellular behavior is proposed.
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Epithelial contact guidance on well-defined micro- and nanostructured substrates
TL;DR: This work documents that biologic length-scale topographic features that model features encountered in the native basement membrane can profoundly affect epithelial cell behavior.
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Indentation versus tensile measurements of Young's modulus for soft biological tissues.
TL;DR: On average, YM values for soft tissues are consistently lower when obtained by indentation deformations, and the implications and potential impact of this finding are discussed.
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Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice
Garet P. Lahvis,Susanne L. Lindell,Russell S. Thomas,Robert S. McCuskey,Christopher J. Murphy,E.W.N. Glover,Michael L. Bentz,James H. Southard,Christopher A. Bradfield +8 more
TL;DR: Upon investigating the liver phenotype, it was found that the decrease in liver size is directly related to a reduction in hepatocyte size and the result of massive portosystemic shunting in null animals.
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Endotoxin-Induced Structural Transformations in Liquid Crystalline Droplets
I-Hsin Lin,Daniel S. Miller,Paul J. Bertics,Christopher J. Murphy,Juan J. de Pablo,Nicholas L. Abbott +5 more
TL;DR: The sensitivity of the LC to endotoxin was measured to change by six orders of magnitude with the geometry of theLC (droplet versus slab), supporting the hypothesis that interactions of endotoxin with topological defects in the LC mediate the response of the droplets.