Showing papers by "Christopher J. O'Donnell published in 1994"
TL;DR: This study hypothesized that simple clinical variables could be used to develop a prediction rule to identify patients after myocardial infarction with a high likelihood of having preserved left ventricular systolic function and aimed to restrict assessment of LVEF to those patients most likely to benefit from the resulting information.
Abstract: Objective: To derive and validate a clinical prediction rule that identifies patients after myocardial infarction who have preserved left ventricular systolic function. Design: Retrospective analys...
40 citations
TL;DR: The GustO investigators dispute the statement that no thrombolytic regimen in the GUSTO trial showed any mortality advantage for patients treated 4 or more hours after symptom onset, a critical issue because most patients with acute myocardial infarction in the United States come to the hospital during this time frame.
Abstract: Open and informed evaluation of study results is essential to advancing scientific understanding, particularly in large-scale trials (such as the Global Utilization of Streptokinase and Tissue Plas...
27 citations