C
Constantin Caruntu
Researcher at Carol Davila University of Medicine and Pharmacy
Publications - 140
Citations - 3025
Constantin Caruntu is an academic researcher from Carol Davila University of Medicine and Pharmacy. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 28, co-authored 98 publications receiving 1933 citations.
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Journal ArticleDOI
The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma
Cristian Scheau,Ioana Anca Badarau,Raluca Simona Costache,Constantin Caruntu,Gratiela Livia Mihai,Andreea Cristiana Didilescu,Carolina Constantin,Monica Neagu +7 more
TL;DR: The roles of MMPs in the EMT involved in HCC invasion, as well as the ancillary roles that MMP cross-activation and tissue inhibitors play in modulating this process are reviewed.
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Human papilloma virus: Apprehending the link with carcinogenesis and unveiling new research avenues (Review).
Daniel Boda,Anca Oana Docea,Daniela Calina,Mihaela Ilie,Constantin Caruntu,Sabina Zurac,Monica Neagu,Carolina Constantin,Daciana Elena Branisteanu,Vlad Mihai Voiculescu,Charalampos Mamoulakis,George N. Tzanakakis,Demetrios A. Spandidos,Nikolaos Drakoulis,Aristides M. Tsatsakis +14 more
TL;DR: The aim of this comprehensive review was to thoroughly present the updated information on virus development, cancer occurrence, treatment and prevention strategies, in an attempt to shed further light into the field, including novel research avenues.
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Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence.
Bahare Salehi,Cristina Quispe,Imane Chamkhi,Nasreddine El Omari,Abdelaali Balahbib,Javad Sharifi-Rad,Abdelhakim Bouyahya,Muhammad Akram,Mehwish Iqbal,Anca Oana Docea,Constantin Caruntu,Gerardo Leyva-Gómez,Abhijit Dey,Miquel Martorell,Daniela Calina,Víctor López,Francisco Les +16 more
TL;DR: In this article, a review comprehensively describes preclinical studies on chalcones and their derivatives describing their immense significance as antidiabetic, anticancer, anti-inflammatory, antimicrobial, antioxidant, antiparasitic, psychoactive, and neuroprotective agents.
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Chemically induced skin carcinogenesis: Updates in experimental models (Review)
Monica Neagu,Constantin Caruntu,Carolina Constantin,Daniel Boda,Sabina Zurac,Demetrios A. Spandidos,Aristidis Tsatsakis +6 more
TL;DR: This review outlines several aspects regarding the skin toxicity testing domain in mouse models of chemically induced skin carcinogenesis, and using mouse models in preclinical testing is important due to the fact that, at the molecular level, common mechanisms with human cutaneous tumorigenesis are depicted.
Journal ArticleDOI
Inflammation: A key process in skin tumorigenesis (Review)
Monica Neagu,Carolina Constantin,Constantin Caruntu,Carmen Dumitru,Mihaela Surcel,Sabina Zurac +5 more
TL;DR: In skin cancers, inflammatory markers can find their place in the biomarker set for improvement of diagnosis and prognosis, and an abundance of studies focusing on molecular pathways that trigger inflammation-mediated tumorigenesis have revealed a series of biomarkers that can improve the diagnosisand prognosis in oncology.