Cristian Palmiere

TL;DR: A review of the literature pertaining to the diagnostic performance of classical and novel biochemical parameters that may be used in the forensic casework to identify disorders in glucose metabolism focusing on the usefulness of traditional and alternative specimens that can be sampled and subsequently analyzed to diagnose acute complications of diabetes mellitus as causes of death.

TL;DR: Serum C-reactive protein and procalcitonin concentrations were significantly different between sepsis cases and control cases, suggesting that measurement of interleukin-6, interleucin-8, and tumor necrosis factor alpha is non-optimal for postmortem discrimination of cases with sepsi.

TL;DR: A review of the literature pertaining to the diagnostic performance of classical and novel biomarkers of inflammation and bacterial infection in the forensic setting suggests that a combination of biomarkers could more effectively discriminate non-infectious from infectious inflammations.

TL;DR: The vitreous glucose concentration appears to be the most reliable marker to estimate antemortem hyperglycaemia and, along with the determination of other biochemical markers, to confirm diabetic ketoacidosis as the cause of death.

TL;DR: A new headspace-gas chromatography-mass spectrometry method applicable to the routine determination of hydrogen sulfide (H(2)S) concentrations in biological and gaseous samples is presented and a full validation using accuracy profile based on the β-expectation tolerance interval is presented.