Cun Zhang

TL;DR: The findings provide further evidence for the pivotal role of the cerebellum in the neuropathology of depression, pointing to potential targets of cerebellar-cerebral pathways for alternative intervention or monitoring therapeutic responses.

TL;DR: The data indicate that preserved gray matter morphology, impaired white matter integrity, and decreased local synchronization degree yet increased FCS are specific to low SE in MDD patients, which might provide insights into the neural mechanisms of sleep disturbance in depression.

TL;DR: Mediation analyses revealed that the relationships between SE and severity of depression and anxiety symptoms were significantly mediated by the altered rsFC, and low SE-related brain functional alterations were not affected by antidepressant medication and were independent of structural changes.

TL;DR: TIV may serve as a potential neural biomarker for monitoring responses to adjuvant therapy of vitamin D in patients with MDD, and Linear regression analyses showed that TIV and serum vitamin D concentration were significant predictors of HAMD score.

TL;DR: Quantitative comparison analysis revealed that MDD patients exhibited reduced voxel-wise concordance in multiple cortical and subcortical regions, and this was associated with worse performances in prospective memory and sustained attention in the MDD group.