This chapter surveys the progress made during the last thirty years in scaling-up the analytical chromatographic process into preparative and production scale processes for the continuous separation of gas or liquid mixtures. The different design approaches are reviewed and some results from their applications are included to enable some comparisons between the various methods to be drawn. Batch, continuous counter-, cross- and co-current systems have been considered, ranging from small scale to industrial size systems. In addition to chromatographic separators, part of this chapter is also devoted to the use of these systems as chromatographic reactor-separators. This is an important extension to the application of the chromatographic principle, since it opens up new horizons and provides the chemist and the engineer with a new tool in applications where the removal of a reaction product from the reaction mixture causes a shift on the equilibrium of a reversible reaction and results in increased...

Chemical and Biochemical Separations Using Preparative and Large Scale Batch and Continuous Chromatography

Comparison of plate numbers and column lengths in chromatography and distillation

http://link.springer.com/content/pdf/10.1007/978-94-009-8579-7_4.pdf

Design and Optimisation of Preparative Chromatographic Separations

Experimental and theoretical studies of countercurrent solvent-gas extraction—II: The construction and operation of a laboratory differential vapour-absorption column

D.W. Pritchard

Papers

Experimental and theoretical studies of countercurrent solvent-gas extraction—I Continuous gas-chromatography in a laboratory moving-bed column

Experimental and theoretical studies of countercurrent solvent-gas extraction—II: The construction and operation of a laboratory differential vapour-absorption column