Purpose: To study the adverse impacts of ultraviolet radiation-A (UVA 320–400 nm) on some hematological and biochemical parameters of Bufo regularis was considered.Materials and methods: Samples were classified into four groups: (i) Control; (ii) ultraviolet radiation (UVR)-treated group (for 3 days/for 15 min/day); (iii) UVR-treated group (for 3 days/for 30 min/day); and (iv) (for 3 days/for 60 min/day). The destructive effects of UVA radiation was evaluated by red blood cells (RBC) count, hemoglobin content (Hb), hematocrite (Ht), erythrocytic indices, white blood cells (WBC) count, total protein, glucose, aspartic amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), lactate dehyderogenase (LDH), glucose-6-phosphate dehyderogenase (G6PDH) and total bilribuin.Results: No mortality was observed. However, some physiological effects after the exposure to UVA were reported. The UVA-induced malformations recorded in the red blood cells included crenated cells (Cr), Aca...

Hematotoxic and biochemical effects of UVA on the Egyptian toad (Bufo regularis).

The effect of the anticancer drug adriamycin on the morphology of the erythrocytes as well as some blood parameters were studied in the Egyptian toad Bufo regularis. Injecting the toads subcutaneously in the dorsal lymph sac with adriamycin at a dose level of 2 mg/kg body weight once every three weeks for 12 weeks induced the formation of abnormalities in the cytoplasm and nuclei of the erythrocytes. Its administration also caused severe anaemia, since the number of red blood corpuscles, haemoglobin content and haematocrit values were obviously decreased throughout the whole experimental period. The total leucocytic count was also diminished. On the other hand, the erythrocyte sedimentation rate was increased all over the experiment.

Daabees Ay

Papers

Effect of adriamycin on the morphology of the erythrocytes and blood parameters of the toad Bufo regularis.