Showing papers by "Dale G. Renlund published in 2001"
01 Jan 2001
TL;DR: This vascular inflammatory process, often termed acute vascular rejection, is identified in 50% of acutely rejecting kidneys and is frequently associated with allograft injury or loss in spite of increased immunosuppressive therapy.
Abstract: Pathologic descriptions of allograft rejection of solid organs have long recognized several forms of vascular involvement as part of the rejection process. Renal allografts commonly display vasculitis involving the arteries and arterioles of the cortex with or without cellular infiltrates invading tubules in the severest forms of acute rejection.1–3 This vascular inflammatory process, often termed acute vascular rejection, is identified in 50% of acutely rejecting kidneys and is frequently associated with allograft injury or loss in spite of increased immunosuppressive therapy.2–4 By contrast, arteritis is rarely identified in cardiac allografts on endomyocardial biopsy although it has been associated with poor allograft survival.5,6