Damu G. Amooru

TL;DR: The molecular dynamics study makes an important contribution to understanding the effect of the binding of beta-sitosterol on conformational changes of HSA and the stability of a protein-drug complex system in aqueous solution.

TL;DR: N-trans-p-coumaroyltyramine isolated from Physalis minima is a phenolic substance exhibiting many pharmacological activities like potent inhibition of acetyl cholinesterase, cell proliferation, platelet aggregation, and also antioxidant activity, which indicates the hydrophobic interactions of CT with HSA and is in well agreement with the computational calculations and molecular docking studies.

TL;DR: It is suggested that micro TOF-Q mass spectrometry is useful technique for drug binding studies after showing for the first time that BA isolated from a plant (Tephrosia calophylla) binds to HSA.

TL;DR: It is imperative to assign a greater role of HSA's as a carrier molecule for many drugs to understand the interactions of H SA with Trimethoxy flavone, which will be pivotal in the design of new TMF-inspired drugs.

TL;DR: 3-trans-feruloyl maslinic acid, a non-fluorescent derivative of Tetracera asiatica, is extracted from the medicinal plant and found that FMA binds strongly in different places with hydrogen bonding at IB domain of Arg 114, Leu 115 and Asp 173.