Daniel Desmecht

TL;DR: It is formally shown that striated muscle is the production site of functional myostatin and that this member of the TGFβ family of growth and differentiation factors regulates muscle mass not only during early embryogenesis but throughout development, indicating that myostarin antagonist could be used to treat muscle wasting and to promote muscle growth in man and animals.

TL;DR: The results demonstrate that the kinetics of NF-kappaB activity is strongly related to the course of the disease and confirm the relevance ofNF-kappB as a putative target in asthma therapy and uncommon p65 homodimers could transactivate, in BCs, a subset of genes, such as ICAM-1, characteristic of chronic airway inflammation.

TL;DR: Although juvenile nephropathy has been reported in many breeds of dog, this is the first report of the condition in the Collie and the Irish Wolfhound and only the second description in the Boxer and the Rottweiler.

TL;DR: A three-year-old male golden retriever had had progressive dyspnoea, exercise intolerance, stridor, and a modified bark for five months and a mass 2 cm in diameter was present dorsal to the right side of the larynx, consistent with rhabdomyoma.

TL;DR: Bovine mast cells are closer to those of human beings, in which chymase-containing mast cells predominate in connective tissues, including skin, than in rodents, which suggests that more than one chym enzyme subset is present, at least in duodenum.