D
Daniela Bonacker
Researcher at Technical University of Dortmund
Publications - 8
Citations - 551
Daniela Bonacker is an academic researcher from Technical University of Dortmund. The author has contributed to research in topics: Genotoxicity & Micronucleus test. The author has an hindex of 8, co-authored 8 publications receiving 530 citations.
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Journal ArticleDOI
Interaction of metal salts with cytoskeletal motor protein systems.
Ricarda Thier,Daniela Bonacker,Thomas Stoiber,Konrad J. Böhm,Minsheng Wang,Eberhard Unger,Hermann M. Bolt,Gisela H. Degen +7 more
TL;DR: The hypothesis that lead and mercury genotoxicity may result, at least in part, via disturbance of chromosome segregation via interaction with cytoskeletal proteins is supported.
Interaction of metal salts with cytoskeletal motor protein systems
Ricarda Thier,Daniela Bonacker,Thomas Stoiber,Konrad J. Böhm,Minsheng Wang,Eberhard Unger,Hermann M. Bolt,Gisela H. Degen +7 more
TL;DR: In this article, the genotoxic effects of inorganic lead and mercury salts were studied using the MN assay and the CREST analysis in V79 Chinese hamster fibroblasts.
Journal ArticleDOI
Genotoxicity of inorganic mercury salts based on disturbed microtubule function.
Daniela Bonacker,Thomas Stoiber,Minsheng Wang,Konrad J. Böhm,Irina Prots,Eberhard Unger,Ricarda Thier,Hermann M. Bolt,Gisela H. Degen +8 more
TL;DR: The overall data are consistent with the concept that the chromosomal genotoxicity of inorganic mercury could be due to interaction of Hg2+ with the motor protein kinesin mediating cellular transport processes.
Journal ArticleDOI
Genotoxicity of Inorganic Lead Salts and Disturbance of Microtubule Function
Daniela Bonacker,Thomas Stoiber,Konrad J. Böhm,Irina Prots,Minsheng Wang,Eberhard Unger,Ricarda Thier,Hermann M. Bolt,Gisela H. Degen +8 more
TL;DR: The processes reported here point to relevant interactions of lead with tubulin and kinesin at low dose levels, as well as a dose‐dependent effect of lead nitrate on microtubule motility.
Journal ArticleDOI
Disturbed microtubule function and induction of micronuclei by chelate complexes of mercury(II)
Thomas Stoiber,Daniela Bonacker,Konrad J. Böhm,Hermann M. Bolt,Ricarda Thier,Gisela H. Degen,Eberhard Unger +6 more
TL;DR: Mercury(II) has a much higher affinity to sulfhydryls of cytoskeletal proteins than to this type of complexing agents, which indicates that the suitability of EDTA and related compounds for remediation of environmental mercury contamination or for other detoxification purposes involving mercury has to be questioned.